Evidence map›Paper›PMID 39008022›Full record

ReviewCurrent neurology and neuroscience reports2024

Critical Care of Spinal Cord Injury.

Sabrina L Zeller, Alan Stein, Ilya Frid, Austin B Carpenter, Sauson Soldozy, Cameron Rawanduzy, Jon Rosenberg, Andrew Bauerschmidt, Fawaz Al-Mufti, Stephan A Mayer and 2 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current neurology and neuroscience reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. The conserved fibroblast growth factor receptor-based signaling is required for dendrite regeneration.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Review
  7. Perioperative management in acute and chronic spinal cord injury, narrative review.Journal of anesthesia, analgesia and critical care · 2025
    Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sabrina L ZellerDepartment of Neurosurgery, Westchester Medical Center, Valhalla, NY, USA.
Alan SteinDepartment of Neurosurgery, Westchester Medical Center, Valhalla, NY, USA.
Ilya FridDepartment of Neurosurgery, Westchester Medical Center, Valhalla, NY, USA.
Austin B CarpenterDepartment of Neurosurgery, Westchester Medical Center, Valhalla, NY, USA.
Sauson SoldozyDepartment of Neurosurgery, Westchester Medical Center, Valhalla, NY, USA.
Cameron RawanduzyDepartment of Neurosurgery, Westchester Medical Center, Valhalla, NY, USA.
Jon RosenbergDepartment of Neurosurgery, Westchester Medical Center, Valhalla, NY, USA.
Andrew BauerschmidtDepartment of Neurosurgery, Westchester Medical Center, Valhalla, NY, USA.
Fawaz Al-MuftiDepartment of Neurosurgery, Westchester Medical Center, Valhalla, NY, USA.
Stephan A MayerDepartment of Neurosurgery, Westchester Medical Center, Valhalla, NY, USA.
Merritt D KinonDepartment of Neurosurgery, Westchester Medical Center, Valhalla, NY, USA.
John V WainwrightDepartment of Neurosurgery, Westchester Medical Center, Valhalla, NY, USA. john.wainwright@wmchealth.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewSpinal cord injury (SCI) is a major cause of morbidity and mortality, posing a significant financial burden on patients and the healthcare system. While little can be done to reverse the primary mechanical insult, minimizing secondary injury due to ischemia and inflammation and avoiding complications that adversely affect neurologic outcome represent major goals of management. This article reviews important considerations in the acute critical care management of SCI to improve outcomes. RECENT

findingsNeuroprotective agents, such as riluzole, may allow for improved neurologic recovery but require further investigation at this time. Various forms of neuromodulation, such as transcranial magnetic stimulation, are currently under investigation. Early decompression and stabilization of SCI is recommended within 24 h of injury when indicated. Spinal cord perfusion may be optimized with a mean arterial pressure goal from a lower limit of 75-80 to an upper limit of 90-95 mmHg for 3-7 days after injury. The use of corticosteroids remains controversial; however, initiation of a 24-h infusion of methylprednisolone 5.4 mg/kg/hour within 8 h of injury has been found to improve motor scores. Attentive pulmonary and urologic care along with early mobilization can reduce in-hospital complications.

Indexed as

Critical CareSpinal Cord InjuriesHumansNeuroprotective AgentsNeuroprotective AgentsCorticosteroidsCritical careRiluzoleSpinal cord injurySpinal cord perfusion

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.