Evidence map›Paper›PMID 39008014›Full record

ReviewAdvances in neurobiology2024

Synaptic Engram.

Hyunsu Jung, Daehee Han, Chaery Lee, Bong-Kiun Kaang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Advances in neurobiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hyunsu JungCenter for Cognition and Sociality, Life Science Institute, Institute for Basic Science (IBS), Daejeon, South Korea.
Daehee HanCenter for Cognition and Sociality, Life Science Institute, Institute for Basic Science (IBS), Daejeon, South Korea.
Chaery LeeCenter for Cognition and Sociality, Life Science Institute, Institute for Basic Science (IBS), Daejeon, South Korea.
Bong-Kiun KaangCenter for Cognition and Sociality, Life Science Institute, Institute for Basic Science (IBS), Daejeon, South Korea. kaang@ibs.re.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The concept of the engram refers to structural and/or physiological changes that underlie memory associations during learning. However, the precise biological basis of the engram remains elusive, with ongoing controversy regarding whether it resides at the cellular level or within the synaptic connections between activated cells. Here, we briefly review the studies investigating the cellular engram and the challenges they encounter. Subsequently, we delve into the biological basis of the engram within synaptic connections. In this regard, we introduce the history of synaptic engrams and discuss recent findings suggesting that synaptic plasticity serves as a substrate for memory. Additionally, we provide an overview of key technologies utilized in the study of synaptic plasticity.

Indexed as

MemoryNeuronal PlasticitySynapsesAnimalsHumansLearningNeuronsCellular engramCircuitsConnectivityPlasticitySynaptic engram

Identifiers

PMID39008014

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.