Evidence map›Paper›PMID 39007920›Full record

ReviewJournal of neural transmission (Vienna, Austria : 1996)2024

Therapeutic potential of transient receptor potential (TRP) channels in psychiatric disorders.

Veerta Sharma, Prateek Sharma, Thakur Gurjeet Singh

Abstract readReview
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In one paragraph

Review in Journal of neural transmission (Vienna, Austria : 1996), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Veerta SharmaChitkara College of Pharmacy, Chitkara University, Rajpura, 140401, Punjab, India.ORCID 0000-0002-6061-2012
Prateek SharmaChitkara College of Pharmacy, Chitkara University, Rajpura, 140401, Punjab, India.ORCID 0009-0006-3656-669X
Thakur Gurjeet SinghChitkara College of Pharmacy, Chitkara University, Rajpura, 140401, Punjab, India. gurjeet.singh@chitkara.edu.in.ORCID 0000-0003-2979-1590

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psychiatric disorders such as Bipolar disorder, Anxiety, Major depressive disorder, Schizophrenia, Attention-deficit/hyperactivity disorder, as well as neurological disorders such as Migraine, are linked by the evidence of altered calcium homeostasis. The disturbance of intra-cellular calcium homeostasis disrupts the activity of numerous ion channels including transient receptor potential (TRP) channels. TRP channel families comprise non-selective calcium-permeable channels that have been implicated in variety of physiological processes in the brain, as well as in the pathogenesis of psychiatric disorders. Through a comprehensive review of current research and experimentation, this investigation elucidates the role of TRP channels in psychiatric disorders. Furthermore, this review discusses about the exploration of epigenetics and TRP channels in psychiatric disorders.

Indexed as

Mental DisordersTransient Receptor Potential ChannelsAnimalsHumansTransient Receptor Potential ChannelsADHDCalcium signallingPsychiatric disordersSchizophreniaTransient receptor potential (TRP) channels

Identifiers

PMID39007920

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.