Evidence map›Paper›PMID 39007847›Full record

ArticleJournal of periodontology2025

In vivo experimental study comparing alveolar ridge preservation versus guided bone regeneration after unassisted socket healing at intact and damaged sites in narrow alveolar ridges.

Hae Jee Shin, Jin-Young Park, Hsu Kuo Tien, Franz-Josef Strauss, Jae-Kook Cha, Jung-Seok Lee

Abstract readComparative Study
In one paragraph

Article in Journal of periodontology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Impact of the Buccal Dehiscence Morphotype on the Regenerative Strategy in Immediate Implant Placement.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hae Jee ShinDepartment of Periodontology, Research Institute of Periodontal Regeneration, Yonsei University College of Dentistry, Seoul, South Korea.ORCID https://orcid.org/0009-0007-4250-4660
Jin-Young ParkDepartment of Periodontology, Research Institute of Periodontal Regeneration, Yonsei University College of Dentistry, Seoul, South Korea.ORCID https://orcid.org/0000-0002-6408-1618
Hsu Kuo TienDepartment of Periodontology, Research Institute of Periodontal Regeneration, Yonsei University College of Dentistry, Seoul, South Korea.ORCID https://orcid.org/0000-0002-6906-7209
Franz-Josef StraussClinic of Reconstructive Dentistry, University of Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0002-5832-7327
Jae-Kook ChaDepartment of Periodontology, Research Institute of Periodontal Regeneration, Yonsei University College of Dentistry, Seoul, South Korea.
Jung-Seok LeeDepartment of Periodontology, Research Institute of Periodontal Regeneration, Yonsei University College of Dentistry, Seoul, South Korea.ORCID https://orcid.org/0000-0003-1276-5978

Funding

Ministry of Science, ICT & Future Planning 2022R1A2C2005537National Research Foundation of Korea
6 · The paper itself

Abstract

backgroundTo compare bone regeneration and dimensional alteration of alveolar ridge at intact and damaged extraction sockets after alveolar ridge preservation (ARP) and implant placement versus unassisted socket healing followed by guided bone regeneration (GBR) with simultaneous implant placement.

methodsIn 6 beagle dogs, 3 types of extraction sockets in the mandible were created: (1) intact sockets, (2) 1-wall defect sockets and (3) 2-wall defect sockets. The sockets were allocated to undergo either (1) ARP and implant placement 8 weeks later (ARP group) or (2) GBR with simultaneous implant placement after 8 weeks of unassisted socket healing (GBR group). After an additional healing period of 8 weeks, bone regeneration and dimensional changes were evaluated radiographically and histologically.

resultsGBR showed superior bone formation and greater bone gains compared to ARP, regardless of the initial extraction-socket configuration. Although ARP maintained the preexisting alveolar ridge dimensions, peri-implant bone defects were still detected at 8 weeks of follow-up. Histomorphometric analyses confirmed that GBR increased dimensions of the alveolar ridge compared to baseline, and the augmentation and bone regeneration were greater with GBR than with ARP.

conclusionEarly implant placement with ARP can mitigate alveolar ridge changes in the narrow alveolar ridge. However, early implant placement with simultaneous GBR creates the conditions for enhanced bone regeneration around the implant and greater ridge augmentation compared to ARP, irrespective of the extraction-socket configuration.

Indexed as

Alveolar Bone LossAlveolar ProcessAlveolar Ridge AugmentationBone RegenerationGuided Tissue Regeneration, PeriodontalTooth SocketAnimalsBone SubstitutesDental Implantation, EndosseousDental ImplantsDogsFollow-Up StudiesMaleMandibleOsteogenesisTooth ExtractionBone SubstitutesDental Implantsalveolar ridge augmentationanimal modelbone regenerationbone substitutestooth extraction

Identifiers

PMID39007847
PMCPMC11951950

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.