ArticleJournal of speech, language, and hearing research : JSLHR2024
How Do Quantitative Videofluoroscopy Measures Differ Between People With Amyotrophic Lateral Sclerosis and Age-Matched Healthy Adults?
Article in Journal of speech, language, and hearing research : JSLHR, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Swallowing After Open Partial Horizontal Laryngectomy Type IIa: A Quantitative Videofluoroscopic Analysis Using the Analysis of Swallowing, Physiology, Events, Kinematics, and Timing.Journal of speech, language, and hearing research : JSLHR · 2026Article
- White Matter Microstructural Correlates of Swallowing Biomechanics: An Exploratory Pilot Study in Healthy Young Adults.Dysphagia · 2025Article
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Authors and funding
5 authors.
Funding
Abstract
purposeDysphagia is a leading cause of morbidity in people with amyotrophic lateral sclerosis (PwALS). Previous videofluoroscopic swallowing studies (VFSS) in PwALS do not account for the influence of senescence. We aimed to compare swallowing in PwALS and an age- and sex-matched control group using healthy reference data to define typical and atypical values.
methodWe conducted retrospective analysis of VFSS data from 19 PwALS (10 male,
resultsPwALS showed increased frequencies of multiple swallows per bolus, incomplete laryngeal vestibule closure, and reduced hyoid speed across consistencies. By contrast, similar frequencies of atypical values for pharyngeal constriction and residue in both cohorts suggest that age-related changes may contribute to the presence of these features in PwALS.
conclusionsThis analysis builds on previous descriptions of swallowing pathophysiology in amyotrophic lateral sclerosis (ALS) by clarifying the extent to which aging may account for some of the atypical findings seen in this patient population. Longitudinal studies are recommended to further differentiate the effects of ALS from age-related changes in swallowing over the course of disease progression.
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