Evidence map›Paper›PMID 39007563›Full record

ArticleJournal of bacteriology2024

An exopolysaccharide pathway from a freshwater

Alexandra G Goetsch, Daniel Ufearo, Griffin Keiser, Christian Heiss, Parastoo Azadi, David M Hershey

Abstract read
In one paragraph

Article in Journal of bacteriology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Diversification of biofilm architecture among freshwaterApplied and environmental microbiology · 2026
    Article
  2. ACS applied polymer materials · 2026
    Article
  3. Article
  4. Genomic-based taxonomic classification of the orderInternational journal of systematic and evolutionary microbiology · 2025
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Alexandra G GoetschDepartment of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Daniel UfearoDepartment of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Griffin KeiserComplex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA.
Christian HeissComplex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA.
Parastoo AzadiComplex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA.
David M HersheyDepartment of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0001-8745-9524

Funding

Surface adaptation in bacterial cellsR35GM150652 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI David M. Hershey · 2023 to 2026
$1.7M
Arnold and Mabel Beckman Foundation (AMBF) BYI2023HHS | National Institutes of Health (NIH) R35GM150652NIGMS NIH HHS R35 GM150652U.S. Department of Energy (DOE) DE-SC0015662
6 · The paper itself

Abstract

Bacteria embellish their cell envelopes with a variety of specialized polysaccharides. Biosynthesis pathways for these glycans are complex, and final products vary greatly in their chemical structures, physical properties, and biological activities. This tremendous diversity comes from the ability to arrange complex pools of monosaccharide building blocks into polymers with many possible linkage configurations. Due to the complex chemistry of bacterial glycans, very few biosynthetic pathways have been defined in detail. As part of an initiative to characterize novel polysaccharide biosynthesis enzymes, we isolated a bacterium from Lake Michigan called IMPORTANCE: Bacteria produce complex polysaccharides that serve a range of biological functions. These polymers often have properties that make them attractive for industrial applications, but they remain woefully underutilized. In this work, we studied a novel polysaccharide called promonan that is produced by

Indexed as

Multigene FamilyPolysaccharides, BacterialSphingomonasBacterial ProteinsBiosynthetic PathwaysFresh WaterLakesBacterial ProteinsPolysaccharides, BacterialbiopolymerpolysaccharideSphingomonaswzy

Identifiers

PMID39007563
PMCPMC11340318

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.