ArticleImaging neuroscience (Cambridge, Mass.)2023
Family income is not significantly associated with T1w/T2w ratio in the Human Connectome Project in Development.
Article in Imaging neuroscience (Cambridge, Mass.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Distinct spatial associations of adversity with hippocampal macro- and microstructure in early adolescence.bioRxiv : the preprint server for biology · 2026Article
- Longitudinal changes in T1w/T2w estimates of cortical myelin with age and pubertal timing.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Spatial heterogeneity and subtypes of functional connectivity development in youth.Nature communications · 2026Article
- Associations between early life adversity and the development of gray matter macrostructure and microstructure.Psychological medicine · 2025Article
- The role of socioeconomic status in shaping associations between sensory association cortex and prefrontal structure and implications for executive function.Developmental cognitive neuroscience · 2025Article
- A sensorimotor-association axis of thalamocortical connection development.bioRxiv : the preprint server for biology · 2024Article
- Individual differences in T1w/T2w ratio development during childhood.Developmental cognitive neuroscience · 2023Article
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Authors and funding
7 authors.
Funding
Abstract
Growing evidence indicates that brain development varies as a function of family socioeconomic status (SES). Numerous studies have demonstrated that children from low-SES backgrounds have thinner cortex than children from higher-SES backgrounds. A recent study in a large developmental sample found widespread associations between lower SES and greater cortical T1w/T2w ratio-thought to be an indirect proxy for cortical myelin. We evaluated the association of family income with cortical T1w/T2w ratio as a function of age in the Human Connectome Project in Development sample of 989 youth aged 8-21 years. We observed no associations between family income and T1w/T2w ratio that were significant after corrections for multiple comparisons at the region, network, or whole-brain level. Region of practical equivalence (ROPE) analyses were also consistent with the absence of an association between family income and T1w/T2w ratio. We discuss potential methodological sources of inconsistency between this and the previous study examining the same question. While the question of whether family income may influence cortical myelin development remains, these null results may indicate that the association between SES and cortical myelin development may not be as strong as with other aspects of brain structure.
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