Evidence map›Paper›PMID 39006756›Full record

ArticlePhysics and imaging in radiation oncology2024

Bringing online adaptive radiotherapy to a standard C-arm linac.

Maureen L Groot Koerkamp, Gijsbert H Bol, Petra S Kroon, Lean L Krikke, Tessa Harderwijk, Annelies J Zoetelief, Annick Scheeren, Stefan van der Vegt, Annika Plat, Jochem Hes and 19 more

Abstract read
In one paragraph

Article in Physics and imaging in radiation oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Maureen L Groot KoerkampDepartment of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands.
Gijsbert H BolDepartment of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands.
Petra S KroonDepartment of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands.
Lean L KrikkeDepartment of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands.
Tessa HarderwijkDepartment of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands.
Annelies J ZoeteliefDepartment of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands.
Annick ScheerenDepartment of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands.
Stefan van der VegtDepartment of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands.
Annika PlatDepartment of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands.
Jochem HesDepartment of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands.
Ineke B A van GasterenDepartment of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands.
Esmee R T RendersDepartment of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands.
Reijer H A RutgersDepartment of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands.
Saskia W KokDepartment of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands.
Joost van KaamDepartment of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands.
Geja J Schimmel-de KogelDepartment of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands.
Gonda G SikkesDepartment of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands.
Dennis WinkelDepartment of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands.
Michael J van RijsselDepartment of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands.
André J M WopereisDepartment of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands.
Kübra IshakogluDepartment of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands.
Juus L NoteboomDepartment of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands.
Jochem R N van der Voort van ZypDepartment of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands.
Naomi BeckDepartment of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands.
Timo F W SoeterikDepartment of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands.
Sandrine M G van de PolDepartment of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands.
Wietse S C EppingaDepartment of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands.
Corine A van EsDepartment of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands.
Bas W RaaymakersDepartment of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current online adaptive radiotherapy (oART) workflows require dedicated equipment. Our aim was to develop and implement an oART workflow for a C-arm linac which can be performed using standard clinically available tools. A workflow was successfully developed and implemented. Three patients receiving palliative radiotherapy for bladder cancer were treated, with 33 of 35 total fractions being delivered with the cone-beam computed tomography (CBCT)-guided oART workflow. Average oART fraction duration was 24 min from start of CBCT acquisition to end of beam on. This work shows how oART could be performed without dedicated equipment, broadening oART availability for application at existing treatment machines.

Indexed as

Bladder cancerCone-beam computed tomographyImage-guided radiotherapyLinear acceleratorOnline adaptive radiotherapy (oART)

Identifiers

PMID39006756
PMCPMC11239695

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.