Evidence map›Paper›PMID 39006585›Full record

ArticleCureus2024

Prenatal Screening for Chagas Disease in the Province of Guadalajara, Spain.

Marta B Roldán Rodríguez, Mario Pérez-Butragueño, Javier E Blanco González, Ramon Perez Tanoira, Alfonso Ortigado Matamala, Alejadro González Praetorius

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Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Marta B Roldán RodríguezGraduate School, University of Alcala de Henares, Madrid, ESP.
Mario Pérez-ButragueñoPediatrics, Hospital Universitario Infanta Leonor, Madrid, ESP.
Javier E Blanco GonzálezPediatrics, Centro de Salud Azuqueca de Henares, Castilla-La Mancha Health Service (SESCAM), Guadalajara, ESP.
Ramon Perez TanoiraMicrobiology, Hospital Universitario Príncipe de Asturias, Alcalá de Henares, ESP.
Alfonso Ortigado MatamalaPediatric Cardiology, Hospital Universitario de Guadalajara, Guadalajara, ESP.
Alejadro González PraetoriusMicrobiology, Hospital Universitario de Guadalajara, Guadalajara, ESP.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction Chagas disease is caused by the protozoan Trypanosoma cruzi. It is endemic in 21 countries in Central and South America. Spain is the only nonendemic country with the highest number of Chagas disease cases outside the Americas. The only transmission mechanism in Spain is vertical transmission. Materials and methods We reviewed the records of pregnant women from endemic countries who underwent prenatal care at the Hospital Universitario de Guadalajara, from January 1, 2009, to December 31, 2022, to determine the rate of Chagas disease screening and vertical transmission. Results Out of a total of 1,681 pregnant women from endemic countries, prenatal screening was conducted on 316 (18.7%) of them. According to our study, the prevalence of the disease in the population of pregnant women from endemic countries is 0.95% with a 95% confidence interval (ranging from 0.32% to 2.75%), with three out of the 316 screened women testing positive for the disease. All positive cases were among Bolivian women. Vertical transmission was not observed in any of the cases. However, because of the small sample size, this study cannot conclusively determine the vertical transmission rate in the province of Guadalajara. Conclusions Implementing regulated prenatal screening protocols for Chagas disease at regional or national levels is necessary to increase the rate of prenatal screening. Additionally, increasing awareness of this condition among healthcare professionals and at-risk populations could further improve prenatal screening rates and treatment adherence.

Indexed as

chagas diseaseneonatal screeningprenatal diagnosistropical diseasevertical transmission of infectious disease

Identifiers

PMID39006585
PMCPMC11246767

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