Evidence map›Paper›PMID 39006507›Full record

ArticleOxford medical case reports2024

Artemisinin-induced cholestatic liver injury and intrahepatic ductopenia.

Joel Thio, Adam Haig, Ei Phyu Phyu Swe, Paul Nguyen, Kayla Tran, Madhavi Kasi

Abstract readCase Reports
In one paragraph

Article in Oxford medical case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Joel ThioDepartment of Gastroenterology, The Prince Charles Hospital, 627 Rode Road, Brisbane, Queensland 4032, Australia.ORCID https://orcid.org/0000-0002-2969-9447
Adam HaigDepartment of Gastroenterology, The Prince Charles Hospital, 627 Rode Road, Brisbane, Queensland 4032, Australia.
Ei Phyu Phyu SweDepartment of Gastroenterology, The Prince Charles Hospital, 627 Rode Road, Brisbane, Queensland 4032, Australia.
Paul NguyenDepartment of Gastroenterology, The Prince Charles Hospital, 627 Rode Road, Brisbane, Queensland 4032, Australia.
Kayla TranDepartment of Anatomical Pathology, Pathology Queensland, The Prince Charles Hospital, 627 Rode Road, Brisbane, Queensland 4032, Australia.
Madhavi KasiDepartment of Gastroenterology, The Prince Charles Hospital, 627 Rode Road, Brisbane, Queensland 4032, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Artemisinin, an ancient Chinese herbal remedy known colloquially as "Qinghao", is now used as treatment for malaria as recommended by the World Health Organisation. There have been few reports of artemisinin-induced liver injury. Most of these instances of hepatotoxicity are reportedly due to prolonged use of herbal remedies containing artemisinin. To our knowledge, we report the first case of intrahepatic ductopenia in a patient with cholestatic liver injury after artemisinin use.

Indexed as

artemisininchemical and drug induced liver injurycholestasisintrahepatic ductopenia

Identifiers

PMID39006507
PMCPMC11246553

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.