Evidence map›Paper›PMID 39006406›Full record

ArticleJCEM case reports2024

A Rare Case of Papillary Thyroid Carcinoma in Marine-Lehnhart Syndrome-Indication for Biopsy of Hot Thyroid Nodules?

Jimmy Masjkur, Martin Thurnheer, Ole Christopher Maas, Roland Schuler, Christopher Strey

Abstract readCase Reports
In one paragraph

Article in JCEM case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Malignancy in toxic thyroid adenoma: Revisiting risk assessment and identifying predictors.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jimmy MasjkureSwiss Medical and Surgical Center, Klinik Stephanshorn, St.Gallen 9000, Switzerland.ORCID https://orcid.org/0000-0002-2340-3879
Martin ThurnheereSwiss Medical and Surgical Center, Klinik Stephanshorn, St.Gallen 9000, Switzerland.
Ole Christopher MaasKlinik für Radiologie und Nuklearmedizin, Kantonsspital St.Gallen, St.Gallen 9000, Switzerland.
Roland SchulerPATHOdiagnostics AG, St.Gallen 9000, Switzerland.
Christopher StreyeSwiss Medical and Surgical Center, Klinik Stephanshorn, St.Gallen 9000, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An uncommon occurrence in which Graves disease (GD) coincides with autonomous functioning thyroid nodules (AFTNs) is termed Marine-Lehnhart syndrome (MLS). While hyperfunctioning nodules in MLS are commonly benign, there exists a rare potential for malignancy. A 41-year-old male patient was initially managed conservatively upon being diagnosed with MLS type 1. However, the emergence of obstructive symptoms prompted a thyroidectomy 4 years after initial presentation. Histological analysis revealed 2 cervical lymph node metastases and papillary thyroid cancer (PTC) within the AFTN.

Indexed as

hot nodule biopsythyroid cancer

Identifiers

PMID39006406
PMCPMC11242449

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.