ArticleFrontiers in veterinary science2024
Seroprevalence of
Article in Frontiers in veterinary science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Evaluation of the Johne's disease surveillance program in dairy herds in Hokkaido, Japan, using a stochastic individual-based simulation model.The Journal of veterinary medical science · 2026Article
- Nationwide seroprevalence of paratuberculosis in indigenous Turkish goat breeds reveals extensive herd-level circulation and breed-associated risk.Irish veterinary journal · 2026Article
- Age-adjusted ELISA cutoffs for Johne's disease in young adult dairy cattle using Bayesian nonparametric models.Frontiers in veterinary science · 2026Article
- Estimated true prevalence and associated risk factors of bovine paratuberculosis antibodies in dairy herds in Bangladesh.PloS one · 2026Article
- The Analysis of Paratuberculosis Prevalence and Associated Performance Parameters in Dairy Cows from Xi'an City.Veterinary sciences · 2025Article
- Exploring the association between Mycobacterium avium subspecies paratuberculosis infection and rheumatoid arthritis: an immunological perspective.Arthritis research & therapy · 2025Article
- Multiplex biomarker-based ELISA enables early detection ofFrontiers in veterinary science · 2025Article
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Authors and funding
8 authors.
Funding
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Abstract
Introduction: Bovine paratuberculosis (PTB) is a chronic enteric disease caused by Methods: To determine the seroprevalence of MAP in Swiss dairy herds and to identify risk factors associated with seropositive herd status and high within-herd seroprevalence, 10,063 serum samples collected from cattle over 12 months of age in 171 Swiss dairy farms were analyzed using a commercial ELISA test. Eight herds were excluded due to non-interpretable ELISA results. Risk factors associated with seropositive herd status and high within-herd seroprevalence were investigated with regression models using results from a questionnaire on management practices possibly associated with the introduction or spread of MAP in the remaining 163 herds. Univariable logistic regression was performed, carrying forward for multivariable regression analysis when Results: The calculated between-herd true seroprevalence was 3.6% (95% CI, 0.96-8.4%). Due to the low within-herd seroprevalence, it was not possible to calculate the true seroprevalence at animal level; the apparent within-herd seroprevalence ranged from 2.3 to 5.5% with a median of 3.6% in nine positive farms. Herd size ( Discussion: These results highlight the limitation of serology for MAP diagnosis in small herds with low infection prevalence.
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Registered trials
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