Evidence map›Paper›PMID 39005432›Full record

ArticlebioRxiv : the preprint server for biology2024

Deep learning identifies heterogeneous subpopulations in breast cancer cell lines.

Tyler A Jost, Andrea L Gardner, Daylin Morgan, Amy Brock

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Tyler A JostDepartment of Biomedical Engineering, The University of Texas at Austin.ORCID 0000-0002-0338-1940
Andrea L GardnerDepartment of Biomedical Engineering, The University of Texas at Austin.
Daylin MorganDepartment of Biomedical Engineering, The University of Texas at Austin.
Amy BrockDepartment of Biomedical Engineering, The University of Texas at Austin.

Funding

Instability of Cancer Cell States in Tumor progression (ICCS)R01CA255536 · NCI · INSTITUTE FOR SYSTEMS BIOLOGY · PI BROCK, AMY, HUANG, SUI · 2021 to 2025
$2.5M
The Allee Effect in Tumor InitiationR01CA226258 · NCI · UNIVERSITY OF TEXAS AT AUSTIN · PI BROCK, AMY, HUANG, SUI · 2018 to 2022
$2.3M
Using label-free Raman microscopy to predict therapeutic resistance of TNBC cellsU01CA253540 · NCI · UNIVERSITY OF TEXAS AT AUSTIN · PI BROCK, AMY, YANKEELOV, THOMAS E · 2020 to 2024
$2.1M
NCI NIH HHS R01 CA226258NCI NIH HHS R01 CA255536NCI NIH HHS U01 CA253540
6 · The paper itself

Abstract

Motivation: Cells exhibit a wide array of morphological features, enabling computer vision methods to identify and track relevant parameters. Morphological analysis has long been implemented to identify specific cell types and cell responses. Here we asked whether morphological features might also be used to classify transcriptomic subpopulations within Results: We demonstrate that cell morphology can reflect underlying transcriptomic differences

Identifiers

PMID39005432
PMCPMC11245002

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.