Evidence map›Paper›PMID 39005284›Full record

ArticlebioRxiv : the preprint server for biology2024

Functional analysis of

Caroline Caetano da Silva, Claudio Macias Trevino, Jason Mitchell, Hemma Murali, Casey Tsimbal, Eileen Dalessandro, Shannon H Carroll, Simren Kochhar, Sarah W Curtis, Ching Hsun Eric Cheng and 7 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors.

Caroline Caetano da SilvaCenter for Craniofacial Innovation, Division of Plastic and Reconstructive Surgery, Department of Surgery, Children's Hospital of Philadelphia, PA, USA.ORCID 0000-0001-9044-7348
Claudio Macias TrevinoHarvard Medical School, Boston, MA, USA.ORCID 0000-0002-3276-2064
Jason MitchellMassachusetts General Hospital, Boston, MA, USA.
Hemma MuraliDepartment of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Casey TsimbalCenter for Craniofacial Innovation, Division of Plastic and Reconstructive Surgery, Department of Surgery, Children's Hospital of Philadelphia, PA, USA.
Eileen DalessandroCenter for Craniofacial Innovation, Division of Plastic and Reconstructive Surgery, Department of Surgery, Children's Hospital of Philadelphia, PA, USA.
Shannon H CarrollCenter for Craniofacial Innovation, Division of Plastic and Reconstructive Surgery, Department of Surgery, Children's Hospital of Philadelphia, PA, USA.
Simren KochharDepartment of Human Genetics, Emory University School of Medicine, Atlanta, GA, USA.
Sarah W CurtisDepartment of Human Genetics, Emory University School of Medicine, Atlanta, GA, USA.
Ching Hsun Eric ChengCenter for Craniofacial Innovation, Division of Plastic and Reconstructive Surgery, Department of Surgery, Children's Hospital of Philadelphia, PA, USA.
Feng WangCenter for Genomic Medicine, Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, PA, USA.
Eric KutscheraCenter for Genomic Medicine, Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, PA, USA.
Russ P CarstensDepartment of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Yi XingCenter for Genomic Medicine, Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, PA, USA.
Kai WangDepartment of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Elizabeth J LeslieDepartment of Human Genetics, Emory University School of Medicine, Atlanta, GA, USA.
Eric C LiaoCenter for Craniofacial Innovation, Division of Plastic and Reconstructive Surgery, Department of Surgery, Children's Hospital of Philadelphia, PA, USA.

Funding

The Intellectual and Developmental Disabilities Research Center (IDDRC) at CHOP/PennP50HD105354 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI ERIC D MARSH, ROBERT Thomas SCHULTZ · 2021 to 2026
$9.2M
Fair Phenotype Annotation and Genomic ReinterpretationR01HG013031 · NHGRI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Wendy K Chung, CHUNHUA WENG · 2023 to 2026
$3.5M
Transfer 5R01DE027983 - Genomic and Functional Analysis of IRF6 Target Genes in Orofacial Cleft PathogenesisR01DE027983 · NIDCR · MASSACHUSETTS GENERAL HOSPITAL · PI LIAO, ERIC CHIEN-WEI · 2019 to 2023
$3.3M
Functional analysis of ESRP1/2 and CTNND1 gene variants in orofacial cleftR01DE032332 · NIDCR · CHILDREN'S HOSP OF PHILADELPHIA · PI Eric Chien-Wei Liao · 2023 to 2026
$2.6M
NHGRI NIH HHS R01 HG013031NICHD NIH HHS P50 HD105354NIDCR NIH HHS R01 DE027983NIDCR NIH HHS R01 DE032332
6 · The paper itself

Abstract

Orofacial cleft (OFC) is a common human congenital anomaly. Epithelial-specific RNA splicing regulators

Identifiers

PMID39005284
PMCPMC11245018

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.