Evidence map›Paper›PMID 39005211›Full record

ArticleCirculation2024

Novel Long Noncoding RNA

Jasmin M Kneuer, Ignacy A Grajek, Melanie Winkler, Stephan Erbe, Tim Meinecke, Ronald Weiss, Tania Garfias-Veitl, Bilal N Sheikh, Ann-Christine König, Maximilian N Möbius-Winkler and 12 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Circulation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Frontiers in genetics · 2025
    Article
  6. Article
  7. From Cell to Gene: Deciphering the Mechanism of Heart Failure With Single-Cell Sequencing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Jasmin M KneuerKlinik und Poliklinik für Kardiologie, Universitätsklinikum Leipzig, Germany (J.M.K., I.A.G., M.W., S.E., T.M., M.N.M.-W., A.K., K.E.K., V.F., S.G., U.L., J.-N.B.).ORCID 0000-0003-0273-3614
Ignacy A GrajekKlinik und Poliklinik für Kardiologie, Universitätsklinikum Leipzig, Germany (J.M.K., I.A.G., M.W., S.E., T.M., M.N.M.-W., A.K., K.E.K., V.F., S.G., U.L., J.-N.B.).
Melanie WinklerKlinik und Poliklinik für Kardiologie, Universitätsklinikum Leipzig, Germany (J.M.K., I.A.G., M.W., S.E., T.M., M.N.M.-W., A.K., K.E.K., V.F., S.G., U.L., J.-N.B.).
Stephan ErbeKlinik und Poliklinik für Kardiologie, Universitätsklinikum Leipzig, Germany (J.M.K., I.A.G., M.W., S.E., T.M., M.N.M.-W., A.K., K.E.K., V.F., S.G., U.L., J.-N.B.).ORCID 0000-0003-0139-8981
Tim MeineckeKlinik und Poliklinik für Kardiologie, Universitätsklinikum Leipzig, Germany (J.M.K., I.A.G., M.W., S.E., T.M., M.N.M.-W., A.K., K.E.K., V.F., S.G., U.L., J.-N.B.).
Ronald WeissInstitute of Clinical Immunology, University of Leipzig, Germany (R.W.).
Tania Garfias-VeitlDepartment of Cardiology and Pneumology, University Medical Center of Göttingen (UMG), Germany (T.G.-V., S.v.H.).ORCID 0000-0003-3672-4046
Bilal N SheikhHelmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, Germany (B.N.S.).ORCID 0000-0002-1970-6236
Ann-Christine KönigGerman Research Center for Environmental Health (GmbH), Metabolomics and Proteomics Core, Helmholtz Zentrum München, Germany (A.-C.K.).ORCID 0000-0001-8265-2499
Maximilian N Möbius-WinklerKlinik und Poliklinik für Kardiologie, Universitätsklinikum Leipzig, Germany (J.M.K., I.A.G., M.W., S.E., T.M., M.N.M.-W., A.K., K.E.K., V.F., S.G., U.L., J.-N.B.).ORCID 0000-0002-4400-3508
Alexander KogelKlinik und Poliklinik für Kardiologie, Universitätsklinikum Leipzig, Germany (J.M.K., I.A.G., M.W., S.E., T.M., M.N.M.-W., A.K., K.E.K., V.F., S.G., U.L., J.-N.B.).ORCID 0000-0002-1842-4480
Karl-Patrik KresojaDepartment of Cardiology, Heart Center at University of Leipzig, Germany (K.-P.K., S.R., H.T., P.L.).ORCID 0000-0002-8616-6751
Sebastian RoschDepartment of Cardiology, Heart Center at University of Leipzig, Germany (K.-P.K., S.R., H.T., P.L.).ORCID 0000-0002-4380-4821
Karoline E KokotKlinik und Poliklinik für Kardiologie, Universitätsklinikum Leipzig, Germany (J.M.K., I.A.G., M.W., S.E., T.M., M.N.M.-W., A.K., K.E.K., V.F., S.G., U.L., J.-N.B.).ORCID 0000-0002-8130-4289
Vanina FilipovaKlinik und Poliklinik für Kardiologie, Universitätsklinikum Leipzig, Germany (J.M.K., I.A.G., M.W., S.E., T.M., M.N.M.-W., A.K., K.E.K., V.F., S.G., U.L., J.-N.B.).ORCID 0000-0003-0854-4750
Susanne GaulKlinik und Poliklinik für Kardiologie, Universitätsklinikum Leipzig, Germany (J.M.K., I.A.G., M.W., S.E., T.M., M.N.M.-W., A.K., K.E.K., V.F., S.G., U.L., J.-N.B.).ORCID 0000-0003-4780-1844
Holger ThieleCentral German Heart Alliance (J.M.K., I.A.G., M.W., S.E., T.M., M.N.M.-W., A.K., K.E.K., V.F., S.G., H.T., U.L., J.-N.B.).ORCID 0000-0002-0169-998X
Philipp LurzDepartment of Cardiology, Heart Center at University of Leipzig, Germany (K.-P.K., S.R., H.T., P.L.).ORCID 0000-0002-5993-4487
Stephan von HaehlingDepartment of Cardiology and Pneumology, University Medical Center of Göttingen (UMG), Germany (T.G.-V., S.v.H.).ORCID 0000-0002-9818-042X
Thimoteus SpeerMedizinische Klinik 4: Nephrologie, Universitätsklinikum Frankfurt, Frankfurt am Main, Germany (T.S.).ORCID 0000-0002-2491-6393
Ulrich LaufsKlinik und Poliklinik für Kardiologie, Universitätsklinikum Leipzig, Germany (J.M.K., I.A.G., M.W., S.E., T.M., M.N.M.-W., A.K., K.E.K., V.F., S.G., U.L., J.-N.B.).ORCID 0000-0003-2620-9323
Jes-Niels BoeckelKlinik und Poliklinik für Kardiologie, Universitätsklinikum Leipzig, Germany (J.M.K., I.A.G., M.W., S.E., T.M., M.N.M.-W., A.K., K.E.K., V.F., S.G., U.L., J.-N.B.).ORCID 0000-0002-7438-3089

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundActivation of the immune system contributes to cardiovascular diseases. The role of human-specific long noncoding RNAs in cardioimmunology is poorly understood.

methodsSingle-cell sequencing in peripheral blood mononuclear cells revealed a novel human-specific long noncoding RNA called

results

conclusionsThese results characterize a novel endogenous anti-inflammatory pathway that involves the conversion of monocyte subtypes into anti-inflammatory CD16

Indexed as

InflammationMonocytesRNA, Long NoncodingAnimalsFemaleHeart FailureHumansMaleMiceMice, Inbred NODMice, SCIDMiddle AgedMyocardial InfarctionRNA, Long Noncodingheart failuremonocytesregenerationRNA, long noncoding

Identifiers

PMID39005211
PMCPMC11444369

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