Evidence map›Paper›PMID 39005127›Full record

ReviewCurrent medicinal chemistry2025

Advancements in Iron Oxide Nanoparticles for Multimodal Imaging and Tumor Theranostics.

He Liu, Zhiming Zhen, Fengxi Chen, Jiafei Chen, Wei Chen

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Targeting glutathione metabolism for tumor radiosensitization (Review).International journal of molecular medicine · 2026
    Review
  2. Review
  3. Review
  4. Strain-SpecificInternational journal of nanomedicine · 2025
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

He LiuDepartment of Radiology, Southwest Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Zhiming ZhenDepartment of Radiology, Southwest Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Fengxi ChenDepartment of Radiology, Southwest Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Jiafei ChenDepartment of Radiology, Southwest Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Wei ChenDepartment of Radiology, Southwest Hospital, Army Medical University (Third Military Medical University), Chongqing, China.

Funding

Natural Science Foundation of Chongqing, China cstb2022nscq-msx0191
6 · The paper itself

Abstract

The emergence of nanomedicine offers renewed promise in the diagnosis and treatment of diseases. Due to their unique physical and chemical properties, iron oxide nanoparticles (IONPs) exhibit widespread application in the diagnosis and treatment of various ailments, particularly tumors. IONPs have magnetic resonance (MR) T1/T2 imaging capabilities due to their different sizes. In addition, IONPs also have biocatalytic activity (nanozymes) and magnetocaloric effects. They are widely used in chemodynamic therapy (CDT), magnetic hyperthermia treatment (MHT), photodynamic therapy (PDT), and drug delivery. This review outlines the synthesis, modification, and biomedical applications of IONPs, emphasizing their role in enhancing diagnostic imaging (including single-mode and multimodal imaging) and their potential in cancer therapies (including chemotherapy, radiotherapy, CDT, and PDT). Furthermore, we briefly explore the challenges in the clinical application of IONPs, such as surface modification and protein adsorption, and put forward opinions on the clinical transformation of IONPs.

Indexed as

Magnetic Iron Oxide NanoparticlesMultimodal ImagingNeoplasmsTheranostic NanomedicineAnimalsHumansMagnetic Resonance ImagingPhotochemotherapybiological imagingchemotherapy.iron oxide nanoparticlesMagnetic resonance imagingradiotherapytumor therapy

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.