Evidence map›Paper›PMID 39005080›Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2024

Effects of aging on diaphragm hyperemia and blood flow distribution in male and female Fischer 344 rats.

Andrew G Horn, Kiana M Schulze, Judy Muller-Delp, David C Poole, Bradley J Behnke

Abstract readComparative Study
In one paragraph

Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Andrew G HornDepartment of Kinesiology, Kansas State University, Manhattan, Kansas, United States.ORCID 0000-0003-4435-4022
Kiana M SchulzeDepartment of Kinesiology, Kansas State University, Manhattan, Kansas, United States.ORCID 0000-0001-6467-5179
Judy Muller-DelpDepartment of Anatomy and Physiology, Kansas State University, Manhattan, Kansas, United States.ORCID 0000-0001-5322-0611
David C PooleDepartment of Kinesiology, Kansas State University, Manhattan, Kansas, United States.ORCID 0000-0003-2441-3793
Bradley J BehnkeDepartment of Kinesiology, Kansas State University, Manhattan, Kansas, United States.

Funding

Role of Adiponectin in Reversal of Age-related Vascular DysfunctionR01HL166591 · NHLBI · KANSAS STATE UNIVERSITY · PI JUDY M DELP · 2023 to 2026
$1.8M
DO HEART FAILURE AND AGING POTENTIATE DIAPHRAGM VASCULAR DYSFUNCTION?R15AG078060 · NIA · KANSAS STATE UNIVERSITY · PI BEHNKE, BRAD J, POOLE, DAVID C · 2021 to 2021
$456k
Role for Nrf2 and exercise in mitigating pulmonary hypertension-induced vascular dysfunctionF31HL170643 · NHLBI · KANSAS STATE UNIVERSITY · PI SCHULZE, KIANA MARIE · 2023 to 2024
$73k
ROLE OF ANGIOTENSIN-(1-7) AND DIAPHRAGM VASCULAR FUNCTION IN HEART FAILURE AND PROLONGED MECHANICAL VENTILATIONF31HL167618 · NHLBI · KANSAS STATE UNIVERSITY · PI HORN, ANDREW · 2023 to 2024
$72k
HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) 1F31HL167618-02HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) 1F31HL170643-01HHS | NIH | National Institute on Aging (NIA) 1R15AG078060NHLBI NIH HHS F31 HL167618NHLBI NIH HHS F31 HL170643NHLBI NIH HHS R01 HL166591NIA NIH HHS R15 AG078060
6 · The paper itself

Abstract

Aging is associated with inspiratory muscle dysfunction; however, the impact of aging on diaphragm blood flow (BF) regulation, and whether sex differences exist, is unknown. We tested the hypotheses in young animals that diaphragm BF and vascular conductance (VC) would be greater in females and that aging would decrease the diaphragm's ability to increase BF with contractions. Young (4-6 mo) and old (22-24 mo) Fischer 344 rats were divided into four groups: young female (YF,

Indexed as

AgingDiaphragmHyperemiaMuscle ContractionRats, Inbred F344Regional Blood FlowAge FactorsAnimalsFemaleMaleRatsSex CharacteristicsSex Factorscontractile activitymedial costal diaphragmperfusionsex differencesvascular conductance

Identifiers

PMID39005080
PMCPMC11444501

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.