Evidence map›Paper›PMID 39004959›Full record

ArticleCurrent neurovascular research2024

The Safety and Efficacy of Leo Stents with Coiling or Alone for Anterior Cerebral Artery Aneurysms.

Yu Duan, Jun Shen, Xuanfeng Qin, Binbin Xu, Renling Mao, Jian Li, Qinzhu An, Yujun Liao, Fayong Zhang, Gong Chen

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Current neurovascular research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yu DuanDepartment of Neurosurgery, Huadong Hospital, Fudan University, China.
Jun ShenDepartment of Neurology, Huadong Hospital, Fudan University, China.
Xuanfeng QinDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.
Binbin XuDepartment of Neurosurgery, Putuo District People's Hospital, Tongji University, Shanghai, China.
Renling MaoDepartment of Neurosurgery, Huadong Hospital, Fudan University, China.
Jian LiDepartment of Neurosurgery, Huadong Hospital, Fudan University, China.
Qinzhu AnDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.
Yujun LiaoDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.
Fayong ZhangDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.
Gong ChenDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.

Funding

Natural Science Foundation of China 82071313"Project of Famous Medical doctors" of Shanghai Medical College of Fudan University DGF828007/028Shanghai Science and Technology Committee 18411962400
6 · The paper itself

Abstract

introductionTreatment of anterior cerebral artery (ACA) aneurysms is still not well established. The Leo stent with blood flow direction is a retrievable stent for intracranial aneurysms, whereas it needs to be studied clearly in patients with ACA aneurysms.

methodsConsecutive patients with ACA aneurysms were retrospectively enrolled in three neurosurgical centers between January 2016 and October 2021. The data on demographics, aneurysm characteristics, symptom resolution, and postoperative course were collected and analyzed. The aneurysm occlusion status was appraised by Raymond-Ray Occlusion Class (RROC).

resultsA total of 57 patients with ACA aneurysms were included in our study. Immediate postprocedural angiograms showed that 20 aneurysms (35.1%) were in complete occlusion (RROC 1), 26 aneurysms (45.6%) were in near-complete occlusion (RROC 2), 11 aneurysms (19.3%) were in incomplete occlusion (RROC 3). The angiographic follow-up found that the rate of complete occlusion increased to 57.9%, and near-completion and incomplete occlusion dropped to 29.8% and 12.3%, respectively. The angiographic result of the last follow-up improved significantly (Z=- 2.805, P=0.005). Univariate analysis indicated that distal location of aneurysms (Z=4.538, P=0.033) and ruptured aneurysms (χ2=.6120, P=0.032) were potential risk factors for intra-parent artery narrowing. Furthermore, multivariate logistic regression analysis found that A3 aneurysms (95% CI 1.427~32.744, P=0.016) are the key risk factor for intra-parent artery narrowing.

conclusionsThe Leo stent is safe and effective for aneurysms located in ACA circulations. The overall occlusion degree improved during follow-up. A distal, small artery was the risk factor for intra-parent artery narrowing.

Indexed as

Intracranial AneurysmStentsAdultAgedAnterior Cerebral ArteryCerebral AngiographyEmbolization, TherapeuticEndovascular ProceduresFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeaneurysmarterycoilingEndovascular treatmentrisk factor.stent

Identifiers

PMID39004959

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.