Evidence map›Paper›PMID 39004930›Full record

ArticleActa obstetricia et gynecologica Scandinavica2025

Prevalence of fetal anomalies, stillbirth, neonatal morbidity, or mortality in pregnancies complicated by placenta accreta spectrum disorders.

Pedro Viana Pinto, Katarzyna Kawka-Paciorkowska, Maddalena Morlando, Hubert Huras, Magdalena Kołak, Charline Bertholdt, Andrzej Jaworowski, Thorsten Braun, Karin A Fox, Olivier Morel and 5 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta obstetricia et gynecologica Scandinavica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Pedro Viana PintoGynecology Department, Centro Hospitalar e Universitário de São João, Porto, Portugal.ORCID 0000-0001-8464-6594
Katarzyna Kawka-PaciorkowskaDepartment of Perinatology, Poznan University of Medical Sciences, Poznan, Poland.ORCID 0000-0003-4674-0496
Maddalena MorlandoDepartment of Women, Children and of General and Specialized Surgery, University "Luigi Vanvitelli", Naples, Italy.ORCID 0000-0002-1304-7575
Hubert HurasDepartment of Obstetrics and Perinatology, Medical College, Jagiellonian University, Krakow, Poland.ORCID 0000-0001-6661-6893
Magdalena KołakDepartment of Obstetrics and Perinatology, Medical College, Jagiellonian University, Krakow, Poland.ORCID 0000-0002-7822-2434
Charline BertholdtDepartment of Obstetrics, Nancy Regional and University Hospital Center (CHRU), Université de Lorraine, Nancy, France.ORCID 0000-0001-9297-5363
Andrzej JaworowskiDepartment of Obstetrics and Perinatology, Medical College, Jagiellonian University, Krakow, Poland.ORCID 0000-0002-6466-9059
Thorsten BraunDepartment of Obstetrics, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.ORCID 0000-0002-1989-9920
Karin A FoxDivision of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, University of Texas Medical Branch, Galveston, Texas, USA.ORCID 0000-0002-8405-772X
Olivier MorelDepartment of Obstetrics, Nancy Regional and University Hospital Center (CHRU), Université de Lorraine, Nancy, France.ORCID 0000-0001-6359-1328
Alexander PapingDepartment of Obstetrics, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.ORCID 0000-0003-2360-6016
Vedran StefanovicDepartment of Obstetrics and Gynecology, Fetomaternal Medical Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.ORCID 0000-0001-5230-1698
Mina MhallemDepartment of Obstetrics, Clinqiues Universitaires Saint-Luc, Brussels, Belgium.ORCID 0000-0003-3528-2389
Heleen J Van BeekhuizenDepartment of Gynecological Oncology, Erasmus MC Cancer Center, University Medical Center Rotterdam, Rotterdam, The Netherlands.ORCID 0000-0001-8899-7412
IS‐PAS group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPlacenta accreta spectrum disorders (PAS) lead to major complications in pregnancy. While the maternal morbidity associated with PAS is well known, there is less information regarding neonatal morbidity in this setting. The aim of this study is to describe the neonatal outcomes (fetal malformations, neonatal morbidity, twin births, stillbirth, and neonatal death), using an international multicenter database of PAS cases. MATERIAL AND

methodsThis was a prospective, multicenter cohort study based on prospectively collected cases, using the international multicenter database of the International Society for PAS, carried out between January 2020 and June 2022 by 23 centers with experience in PAS care. All PAS cases were included, regardless of whether singleton or multiple pregnancies and were managed in each center according to their own protocols. Data were collected via chart review. Local Ethical Committee approval and Data Use Agreements were obtained according to local policies.

resultsThere were 315 pregnancies eligible for inclusion, with 12 twin pregnancies, comprising 329 fetuses/newborns; 2 cases were excluded due to inconsistency of data regarding fetal abnormalities. For the calculation of neonatal morbidity and mortality, all elective pregnancy terminations were excluded, hence 311 pregnancies with 323 newborns were analyzed. In our cohort, 3 neonates (0.93%) were stillborn; of the 320 newborns delivered, there were 10 cases (3.13%) of neonatal death. The prevalence of major congenital malformations was 4.64% (15/323 newborns), most commonly, cardiovascular, central nervous system, and gastrointestinal tract malformations. The overall prevalence of major neonatal morbidity in pregnancies complicated by PAS was 47/311 (15.1%). There were no stillbirths, neonatal deaths, or fetal malformations in reported twin gestations.

conclusionsAlthough some outcomes may be too rare to detect within our cohort and data should be interpreted with caution, our observational data supports reassuring neonatal outcomes for women with PAS.

Indexed as

Congenital AbnormalitiesPlacenta AccretaStillbirthAdultFemaleHumansInfant, NewbornPregnancyPrevalenceProspective Studiesfetal abnormalitiesneonatal deathPASplacentaplacenta previastillbirth

Identifiers

PMID39004930
PMCPMC12087409

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.