ArticleEcho research and practice2024
Global longitudinal active strain energy density (GLASED): age and sex differences between young and veteran athletes.
Article in Echo research and practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Predictive Effect of Echocardiographic Assessment of Myocardial Efficiency on Martial Arts Performance.Journal of sports science & medicine · 2026Observational
- Left Ventricular Ejection Fraction in Heart Failure-A Parameter to Be Discontinued?Journal of clinical medicine · 2026Review
- The 'myocardial work index' does not measure myocardial work.European heart journal. Imaging methods and practice · 2026Article
- Myocardial active strain energy density and contractance: novel prognostic tools for left ventricular function and cardiovascular risk.European heart journal. Imaging methods and practice · 2025Review
- Global longitudinal active strain energy density (GLASED): a powerful prognostic marker in a community-based cohort.European heart journal. Cardiovascular Imaging · 2024Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGlobal longitudinal active strain energy density (GLASED) is an innovative method for assessing myocardial function and quantifies the work performed per unit volume of the left ventricular myocardium. The GLASED, measured using MRI, is the best prognostic marker currently available. This study aimed to evaluate the feasibility of measuring the GLASED using echocardiography and to investigate potential differences in the GLASED among athletes based on age and sex.
methodsAn echocardiographic study was conducted with male controls, male and female young athletes, and male and female veteran athletes. GLASED was calculated from the myocardial stress and strain.
resultsThe mean age (in years) of the young athletes was 21.6 for males and 21.4 for females, while the mean age of the veteran athletes was 53.5 for males and 54.2 for females. GLASED was found to be highest in young male athletes (2.40 kJ/m
conclusionOur findings demonstrated the feasibility of measuring GLASED using echocardiography. GLASED values were greater in young male athletes than in female athletes and decreased with age, suggesting possible physiological differences in their myocardium. The sex-related differences observed in GLASED values among young athletes were no longer present in veteran athletes. We postulate that measuring the GLASED may serve as a useful additional screening tool for cardiac diseases in athletes, particularly for those with borderline phenotypes of hypertrophic and dilated cardiomyopathies.
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