ArticleJournal of periodontology2024
Peri-implantitis induction and resolution around zirconia versus titanium implants.
Article in Journal of periodontology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Biomechanical evaluation of implant materials and connection designs: a structured narrative review of titanium and zirconia.Odontology · 2026Review
- Peri-Implantitis and Periodontitis: Biological Convergence, Contextual Divergence.Journal of periodontal research · 2026Review
- Zirconia and Titanium Implants Placed at Two Supracrestal Levels in Fresh Extraction Socket: Canine Periodontitis Model.Clinical implant dentistry and related research · 2026Article
- Biofilm removal capacity and titanium surface integrity in non-abrasive versus abrasive peri-implantitis cleaning interventions.Journal of periodontology · 2026Article
- Peri-implantitis induction and resolution around zirconia versus titanium implants.Journal of periodontology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
backgroundThis study compared titanium and zirconia implant ligature-induced peri-implant defect progression and response to regenerative surgical intervention.
methodsEight tissue-level endosseous implants were placed in 6 mixed-breed foxhounds, with 2 zirconia and 2 titanium alternating in each hemimandible. Cotton ligatures were placed subgingivally for 16 weeks followed by 8 weeks of spontaneous progression. Standardized radiographs were captured every 2 weeks to evaluate the rate of bone loss. Regenerative surgery was performed utilizing water-jet decontamination, enamel matrix derivative, and locally harvested autogenous bone. After 16 weeks of healing, final radiographic bone levels as well as probing depths, recession, and clinical attachment levels were assessed.
resultsAll 48 implants integrated successfully. The final average post-ligature radiographic defects were 2.88 and 3.05 mm for titanium and zirconia implants, respectively. There was no significant difference between materials in the rate of radiographic bone loss (p = 0.09). Following regenerative surgery, the total average amount of radiographic bone gain was 1.41 and 1.20 mm for titanium and zirconia, respectively. The percentage of defect fill was 51.56% and 37.98% (p = 0.03) for titanium and zirconia, respectively. Inter-group differences were minimal for clinical parameters at the time of sacrifice including periodontal pocket depths (p = 0.81), recession (p = 0.98), or clinical attachment levels (p = 0.51).
conclusionsNo significant difference was found in the rate of peri-implant defect development between titanium and zirconia implants. Both materials gained significant radiographic bone following regenerative surgery with significantly greater defect percentage fill in titanium implants. The final clinical parameters were similar in both groups.
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Registered trials
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