Evidence map›Paper›PMID 39003481›Full record

ArticleTrials2024

Optimising a digitally delivered behavioural weight loss programme: study protocol for a factorial cluster randomised controlled trial.

Gina M Wren, Dimitrios A Koutoukidis, Jadine Scragg, Grace Preston, Marianne Hennessy, Daisy Estephane, Michael Whitman, Susan A Jebb

Abstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gina M WrenNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK. gina.wren@phc.ox.ac.uk.ORCID http://orcid.org/0000-0001-9262-7043
Dimitrios A KoutoukidisNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Jadine ScraggNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Grace PrestonSecond Nature, London, UK.
Marianne HennessySecond Nature, London, UK.
Daisy EstephaneSecond Nature, London, UK.
Michael WhitmanSecond Nature, London, UK.
Susan A JebbNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.

Funding

Medical Research Council MR/R015708/1
6 · The paper itself

Abstract

backgroundDigitally delivered weight loss programmes can provide a convenient, potentially cheaper, and scalable treatment option for people who may need to lose weight. However, outcomes are often inferior to in-person interventions in the long-term. This trial will use principles from the Multiphase Optimisation Strategy (MOST) framework to test whether it can enhance the effectiveness of a commercial digital behavioural weight loss programme. This trial aims to identify an optimised combination of four intervention components to enhance weight loss over a 24-week period. We will also explore which components contribute to improvements in participant retention and engagement with the programme.

methodsApproximately 1400 adults with a BMI > 21 kg/m DISCUSSION: The factorial design is an efficient way to test the efficacy of behavioural components alone, or in combination, to improve the effectiveness of digital weight loss programmes. This trial will test the implementation of the MOST framework in an industry setting, using routinely collected data, which may provide a better way to refine and evaluate these types of interventions in a model of continuous service improvement.

trial registrationTrial registration: ISRCTN, ISRCTN14407868. Registered 5 January 2024, 10.1186/ISRCTN14407868.

Indexed as

Behavior TherapyRandomized Controlled Trials as TopicWeight LossWeight Reduction ProgramsAdultFemaleHealth BehaviorHumansObesityTime FactorsTreatment OutcomeDigital healthmHealthMobile healthMOST frameworkMulticomponentObesityOptimisationOverweightWeight loss

Identifiers

PMID39003481
PMCPMC11245776

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.