Evidence map›Paper›PMID 39003250›Full record

ReviewFEMS microbiology reviews2024

Mechanisms of host adaptation by bacterial pathogens.

Matthew F Barber, J Ross Fitzgerald

Abstract readReview
In one paragraph

Review in FEMS microbiology reviews, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. GutGut microbes · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Host adaptation inApplied and environmental microbiology · 2026
    Review
  9. Article
  10. Article
  11. Review
  12. Visual Screening of Genetic Polymorphisms inSensors (Basel, Switzerland) · 2026
    Article
  13. Article
  14. Host-Driven Genetic Diversity ofTransboundary and emerging diseases · 2026
    Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. The anti-inflammatory drug celecoxib is metabolized by Pseudomonas aeruginosa CYP107S1 in vitro and in vivo.Drug metabolism and disposition: the biological fate of chemicals · 2025
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Matthew F BarberInstitute of Ecology and Evolution, University of Oregon, Eugene, OR 97403, United States.ORCID 0000-0003-2008-2165
J Ross FitzgeraldThe Roslin Institute, University of Edinburgh, Midlothian, EH25 9RG, United Kingdom.

Funding

Molecular mechanisms of evolution at the host-microbe interfaceR35GM133652 · NIGMS · UNIVERSITY OF OREGON · PI BARBER, MATTHEW FREDERICK · 2019 to 2023
$1.8M
Host range determinants of bacterial exfoliative toxinsR21AI173839 · NIAID · UNIVERSITY OF OREGON · PI BARBER, MATTHEW FREDERICK · 2023 to 2024
$406k
Biotechnology and Biological Sciences Research Council BB/W014920/1Medical Research Council MR/X020223/1NIAID NIH HHS R21 AI173839NIGMS NIH HHS R35 GM133652US National Institutes of Health R35GM133652Wellcome TrustWellcome Trust 201531/Z/16/Z
6 · The paper itself

Abstract

The emergence of new infectious diseases poses a major threat to humans, animals, and broader ecosystems. Defining factors that govern the ability of pathogens to adapt to new host species is therefore a crucial research imperative. Pathogenic bacteria are of particular concern, given dwindling treatment options amid the continued expansion of antimicrobial resistance. In this review, we summarize recent advancements in the understanding of bacterial host species adaptation, with an emphasis on pathogens of humans and related mammals. We focus particularly on molecular mechanisms underlying key steps of bacterial host adaptation including colonization, nutrient acquisition, and immune evasion, as well as suggest key areas for future investigation. By developing a greater understanding of the mechanisms of host adaptation in pathogenic bacteria, we may uncover new strategies to target these microbes for the treatment and prevention of infectious diseases in humans, animals, and the broader environment.

Indexed as

BacteriaHost-Pathogen InteractionsAnimalsBacterial InfectionsBacterial Physiological PhenomenaHost AdaptationHumansImmune Evasionadaptationbacteriaevolutionhostinfectionpathogen

Identifiers

PMID39003250
PMCPMC11308195

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.