ArticleBiotechnology letters2024
From yeast screening for suitability as single cell protein to fed-batch cultures.
Article in Biotechnology letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Microbial Hydrolysates as Amino Acid Source in Cell Culture Media for Cellular Agriculture.Biotechnology and bioengineering · 2026Review
- Optimization of fermentation parameters for the valorization of tomato pomace into biomass to produce single cell protein using Saccharomyces cerevisiae.Bioresources and bioprocessing · 2026Article
- Screening of wild-typeFood science and biotechnology · 2026Article
- From beet molasses to malic acid: holistic development of fermentation and downstream process.Biotechnology for biofuels and bioproducts · 2026Article
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Authors and funding
4 authors.
Funding
Abstract
purposeFed-batch cultures have rarely been used in single cell protein (SCP) research. This work evaluated multiple yeast species for suitability as SCP cultivated using glucose- and sucrose-based substrate and performed in-depth studies of fed-batch SCP cultivation kinetics for selected yeasts, including determination of specific crude nitrogen-to-protein conversion factors.
methodsSCP was cultivated using fully synthetic media in flask batch or bioreactor fed-batch cultures. Crude nitrogen and nucleic acid content were determined using the Dumas method and fluorescence assay kits, respectively.
resultsC. utilis compared favorably to other yeasts in flask batch cultures in terms of process yield (0.52 ± 0.01 g
conclusionThis study demonstrated the suitability of C. utilis as SCP, notably the robustness of its crude nitrogen content (as an indicator of protein content) across batch and fed-batch conditions, compared to that of the benchmark yeast S. cerevisiae.
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