Evidence map›Paper›PMID 39001825›Full record

Observational studyJournal of neurotrauma2024

Extent of Traumatic Spinal Cord Injury Is Lesion Level Dependent and Predictive of Recovery: A Multicenter Neuroimaging Study.

Simon Schading-Sassenhausen, Dario Pfyffer, Lynn Farner, Andreas Grillhösl, Orpheus Mach, Doris Maier, Lukas Grassner, Iris Leister, Armin Curt, Patrick Freund

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of neurotrauma, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Tissue bridges offer valuable insights into bladder and bowel outcomes in chronic cervical spinal cord injury.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Simon Schading-SassenhausenSpinal Cord Injury Center, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.ORCID 0000-0003-3969-193X
Dario PfyfferSpinal Cord Injury Center, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
Lynn FarnerSpinal Cord Injury Center, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
Andreas GrillhöslSpinal Cord Injury Center, BG Trauma Center Murnau, Murnau, Germany.
Orpheus MachSpinal Cord Injury Center, BG Trauma Center Murnau, Murnau, Germany.
Doris MaierSpinal Cord Injury Center, BG Trauma Center Murnau, Murnau, Germany.
Lukas GrassnerSpinal Cord Injury Center, BG Trauma Center Murnau, Murnau, Germany.
Iris LeisterSpinal Cord Injury Center, BG Trauma Center Murnau, Murnau, Germany.ORCID 0000-0002-5963-0598
Armin CurtSpinal Cord Injury Center, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
Patrick FreundSpinal Cord Injury Center, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.

Funding

Characterization of central pain mechanisms using simultaneous spinal cord-brain functional imagingR01NS109450 · NINDS · STANFORD UNIVERSITY · PI GLOVER, GARY H, MACKEY, SEAN C · 2018 to 2022
$2.9M
NINDS NIH HHS R01 NS109450
6 · The paper itself

Abstract

Assessing the extent of the intramedullary lesion after spinal cord injury (SCI) might help to improve prognostication. However, because the neurological level of injury impacts the recovery potential of SCI patients, the question arises whether lesion size parameters and predictive models based on those parameters are affected as well. In this retrospective observational study, the extent of the intramedullary lesion between individuals who sustained cervical and thoracolumbar SCI was compared, and its relation to clinical recovery was assessed. In total, 154 patients with subacute SCI (89 individuals with cervical lesions and 65 individuals with thoracolumbar lesions) underwent conventional clinical magnetic resonance imaging 1 month after injury and clinical examination at 1 and 12 months. The morphology of the focal lesion within the spinal cord was manually assessed on the midsagittal slice of T

Indexed as

Magnetic Resonance ImagingRecovery of FunctionSpinal Cord InjuriesAdolescentAdultAgedCervical VertebraeFemaleHumansMaleMiddle AgedNeuroimagingPredictive Value of TestsPrognosisRetrospective StudiesThoracic VertebraebiomarkerMRIrecovery predictionspinal cord injury

Identifiers

PMID39001825
PMCPMC12054703

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.