Evidence map›Paper›PMID 39001553›Full record

ArticleCancers2024

Enhancing Immunotherapy Response Prediction in Metastatic Lung Adenocarcinoma: Leveraging Shallow and Deep Learning with CT-Based Radiomics across Single and Multiple Tumor Sites.

Cécile Masson-Grehaigne, Mathilde Lafon, Jean Palussière, Laura Leroy, Benjamin Bonhomme, Eva Jambon, Antoine Italiano, Sophie Cousin, Amandine Crombé

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cécile Masson-GrehaigneDepartment of Diagnostic and Interventional Oncologic Imaging, Institut Bergonié, F-33076 Bordeaux, France.
Mathilde LafonDepartment of Medical Oncology, Institut Bergonié, F-33076 Bordeaux, France.
Jean PalussièreDepartment of Diagnostic and Interventional Oncologic Imaging, Institut Bergonié, F-33076 Bordeaux, France.
Laura LeroyDepartment of Medical Oncology, Institut Bergonié, F-33076 Bordeaux, France.
Benjamin BonhommeDepartment of Biopathology, Institut Bergonié, F-33076 Bordeaux, France.ORCID 0000-0002-5082-1347
Eva JambonDepartment of Radiology, Pellegrin University Hospital, F-33000 Bordeaux, France.ORCID 0000-0001-5002-472X
Antoine ItalianoDepartment of Medical Oncology, Institut Bergonié, F-33076 Bordeaux, France.
Sophie CousinDepartment of Medical Oncology, Institut Bergonié, F-33076 Bordeaux, France.
Amandine CrombéDepartment of Diagnostic and Interventional Oncologic Imaging, Institut Bergonié, F-33076 Bordeaux, France.ORCID 0000-0003-0098-6482

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to evaluate the potential of pre-treatment CT-based radiomics features (RFs) derived from single and multiple tumor sites, and state-of-the-art machine-learning survival algorithms, in predicting progression-free survival (PFS) for patients with metastatic lung adenocarcinoma (MLUAD) receiving first-line treatment including immune checkpoint inhibitors (CPIs). To do so, all adults with newly diagnosed MLUAD, pre-treatment contrast-enhanced CT scan, and performance status ≤ 2 who were treated at our cancer center with first-line CPI between November 2016 and November 2022 were included. RFs were extracted from all measurable lesions with a volume ≥ 1 cm

Indexed as

deep learninglung adenocarcinomamachine learningmetastasisradiomicsresponse evaluation

Identifiers

PMID39001553
PMCPMC11240700

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.