Evidence map›Paper›PMID 39001529›Full record

ArticleCancers2024

Real-World Clinical Utility of Targeted RNA Sequencing in Leukemia Diagnosis and Management.

Seo Wan Kim, Namsoo Kim, Yu Jeong Choi, Seung-Tae Lee, Jong Rak Choi, Saeam Shin

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Seo Wan KimDepartment of Laboratory Medicine, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Namsoo KimDepartment of Laboratory Medicine, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0002-1098-4782
Yu Jeong ChoiDepartment of Laboratory Medicine, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Seung-Tae LeeDepartment of Laboratory Medicine, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Jong Rak ChoiDepartment of Laboratory Medicine, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Saeam ShinDepartment of Laboratory Medicine, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0003-1501-3923

Funding

National Research Foundation of Korea NRF-2021R1I1A1A01045980
6 · The paper itself

Abstract

Gene fusions are key drivers in acute leukemia, impacting diagnosis and treatment decisions. We analyzed 264 leukemia patients using targeted RNA sequencing with conventional karyotyping and reverse transcription polymerase chain reaction (RT-PCR). Leukemic fusions were detected in 127 patients (48.1%). The new guidelines introduced additional diagnostic criteria, expanding the spectrum of gene fusions. We discovered three novel fusions (

Indexed as

acute leukemiagene fusionkaryotypingRNA sequencing

Identifiers

PMID39001529
PMCPMC11240350

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.