Evidence map›Paper›PMID 39001516›Full record

ArticleCancers2024

Statistical Analysis of Gastric Cancer Cells Response to Broadband Terahertz Radiation with and without Contrast Nanoparticles.

Oliver Daniel Schreiner, Diana Socotar, Romeo Cristian Ciobanu, Thomas Gabriel Schreiner, Bogdan Ionel Tamba

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Oliver Daniel SchreinerDepartment of Electrical Measurements and Materials, Gheorghe Asachi Technical University, 700050 Iasi, Romania.
Diana SocotarDepartment of Electrical Measurements and Materials, Gheorghe Asachi Technical University, 700050 Iasi, Romania.
Romeo Cristian CiobanuDepartment of Electrical Measurements and Materials, Gheorghe Asachi Technical University, 700050 Iasi, Romania.
Thomas Gabriel SchreinerCEMEX-Center for Experimental Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 700259 Iasi, Romania.ORCID 0000-0002-4495-4004
Bogdan Ionel TambaCEMEX-Center for Experimental Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 700259 Iasi, Romania.ORCID 0000-0001-9868-1999

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The paper describes the statistical analysis of the response of gastric cancer cells and normal cells to broadband terahertz radiation up to 4 THz, both with and without the use of nanostructured contrast agents. The THz spectroscopy analysis was comparatively performed under the ATR procedure and transmission measurement procedure. The statistical analysis was conducted towards multiple pairwise comparisons, including a support medium (without cells) versus a support medium with nanoparticles, normal cells versus normal cells with nanoparticles, and, respectively, tumor cells versus tumor cells with nanoparticles. When generally comparing the ATR procedure and transmission measurement procedure for a broader frequency domain, the differentiation between normal and tumor cells in the presence of contrast agents is superior when using the ATR procedure. THz contrast enhancement by using contrast agents derived from MRI-related contrast agents leads to only limited benefits and only for narrow THz frequency ranges, a disadvantage for THz medical imaging.

Indexed as

broadband terahertz spectroscopycancer cells detectioncontrast nanoparticlesstatistical analysisWilcoxon signed-rank test

Identifiers

PMID39001516
PMCPMC11240478

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.