Evidence map›Paper›PMID 39001473›Full record

ArticleCancers2024

Somatic Mutations in KEAP1-NRF2 Complex in Breast Cancer.

Micaela Almeida, Catarina L Ferreira, Rosa Maria Tomé, José Fonseca-Moutinho, António Polónia, Ana Cristina Ramalhinho, Luiza Breitenfeld

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Micaela AlmeidaHealth Sciences Research Centre (CICS), Faculty of Health Sciences, University of Beira Interior (UBI), Avenida Infante D. Henrique, 6200-506 Covilhã, Portugal.
Catarina L FerreiraHealth Sciences Research Centre (CICS), Faculty of Health Sciences, University of Beira Interior (UBI), Avenida Infante D. Henrique, 6200-506 Covilhã, Portugal.ORCID 0000-0002-6858-2604
Rosa Maria ToméClinical Academic Centre of Beiras (CACB), Edifício UBImedical, Estrada Municipal 506, 6200 Covilhã, Portugal.
José Fonseca-MoutinhoHealth Sciences Research Centre (CICS), Faculty of Health Sciences, University of Beira Interior (UBI), Avenida Infante D. Henrique, 6200-506 Covilhã, Portugal.
António PolóniaDepartment of Pathology, Ipatimup Diagnostics, Rua Júlio Amaral de Carvalho, 45, 4200-135 Porto, Portugal.ORCID 0000-0001-8312-1681
Ana Cristina RamalhinhoHealth Sciences Research Centre (CICS), Faculty of Health Sciences, University of Beira Interior (UBI), Avenida Infante D. Henrique, 6200-506 Covilhã, Portugal.ORCID 0000-0003-4783-665X
Luiza BreitenfeldHealth Sciences Research Centre (CICS), Faculty of Health Sciences, University of Beira Interior (UBI), Avenida Infante D. Henrique, 6200-506 Covilhã, Portugal.

Funding

Fundação para a Ciência e Tecnologia Doi: 10.54499/UIDB/00709/2020Fundação para a Ciência e Tecnologia Doi: 10.54499/UIDP/00709/2020Fundação para a Ciência e Tecnologia PTDC/DTPPIC/ 4743/2014Fundação para a Ciência e Tecnologia SFRH/BD146395/2019
6 · The paper itself

Abstract

Breast cancer remains the leading cause of cancer deaths for women. Long-term estrogen exposure is considered carcinogenic due to semiquinone production and to compromised detoxification. Metabolic regulator polymorphisms, such as

Indexed as

breast cancerKEAP1NRF2

Identifiers

PMID39001473
PMCPMC11240725

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.