Evidence map›Paper›PMID 39001470›Full record

ArticleCancers2024

Impact of Neoadjuvant Treatment on Body Composition in Patients with Locally Advanced Gastric Cancer.

Luz Divina Juez, Pablo Priego, Marta Cuadrado, Luis A Blázquez, Silvia Sánchez-Picot, Pablo Gil, Federico Longo, Julio Galindo, José María Fernández-Cebrián, José I Botella-Carretero

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Luz Divina JuezDepartment of General and Digestive Surgery, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.
Pablo PriegoDepartment of General and Digestive Surgery, Hospital Universitario La Paz, 28046 Madrid, Spain.
Marta CuadradoDepartment of General and Digestive Surgery, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.ORCID 0000-0001-6843-8322
Luis A BlázquezDepartment of General and Digestive Surgery, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.ORCID 0000-0001-9424-3908
Silvia Sánchez-PicotDepartment of General and Digestive Surgery, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.
Pablo GilDepartment of General and Digestive Surgery, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.
Federico LongoInstituto Ramón y Cajal de Investigación Sanitaria, IRyCIS, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.
Julio GalindoDepartment of General and Digestive Surgery, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.
José María Fernández-CebriánDepartment of General and Digestive Surgery, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.
José I Botella-CarreteroInstituto Ramón y Cajal de Investigación Sanitaria, IRyCIS, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.ORCID 0000-0002-6425-2747

Funding

Abbott Nutrition (United States) 2024/0193Sociedad Española de Nutrición Clínica y Metabolismo PI2023/0087
6 · The paper itself

Abstract

Neoadjuvant chemotherapy (NT) followed by radical surgery is the standard treatment for locally advanced gastric cancer (GC). The incidence of sarcopenia in upper gastrointestinal tract malignancies is very high, and it may be increased after NT. This study aimed to evaluate the impact of NT on body composition. A retrospective study of patients with locally advanced GC undergoing gastrectomy who had received NT in a tertiary hospital between 2012 and 2019 was conducted. CT measured the skeletal muscle index, total psoas area, and visceral and subcutaneous adipose tissue before and after NT. Of the 180 gastrectomies for GC, 61 patients received NT. During NT, changes in body composition were observed with a decrease in the skeletal muscle mass index (SMMI -2.5%;

Indexed as

cancergastrectomygastricneoadjuvantsarcopenia

Identifiers

PMID39001470
PMCPMC11240361

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.