Evidence map›Paper›PMID 39001459›Full record

ReviewCancers2024

A New Vista of Aldehyde Dehydrogenase 1A3 (ALDH1A3): New Specific Inhibitors and Activity-Based Probes Targeting ALDH1A3 Dependent Pathways in Glioblastoma, Mesothelioma and Other Cancers.

Lorenzo Magrassi, Giulia Pinton, Sabino Luzzi, Sergio Comincini, Andrea Scravaglieri, Valentina Gigliotti, Bianca Laura Bernardoni, Ilaria D'Agostino, Francesca Juretich, Concettina La Motta and 1 more

Abstract readReview
In one paragraph

Review in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. ALDH1A3 Inhibition byIranian journal of pharmaceutical research : IJPR
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lorenzo MagrassiNeurosurgery, Dipartimento di Scienze Clinico-Chirurgiche e Pediatriche, Università degli Studi di Pavia, Fondazione IRCCS Policlinico S. Matteo, 27100 Pavia, Italy.ORCID 0000-0002-8308-2720
Giulia PintonDepartment of Scienze del Farmaco, University of Piemonte Orientale, Via Bovio 6, 28100 Novara, Italy.
Sabino LuzziNeurosurgery, Dipartimento di Scienze Clinico-Chirurgiche e Pediatriche, Università degli Studi di Pavia, Fondazione IRCCS Policlinico S. Matteo, 27100 Pavia, Italy.ORCID 0000-0002-1381-8528
Sergio CominciniDipartimento di Biologia e Biotecnologie, Università di Pavia, 27100 Pavia, Italy.ORCID 0000-0001-7568-1144
Andrea ScravaglieriNeurosurgery, Dipartimento di Scienze Clinico-Chirurgiche e Pediatriche, Università degli Studi di Pavia, Fondazione IRCCS Policlinico S. Matteo, 27100 Pavia, Italy.
Valentina GigliottiDepartment of Scienze del Farmaco, University of Piemonte Orientale, Via Bovio 6, 28100 Novara, Italy.
Bianca Laura BernardoniDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.ORCID 0000-0002-8094-5965
Ilaria D'AgostinoDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.ORCID 0000-0002-4870-7326
Francesca JuretichDepartment of Scienze del Farmaco, University of Piemonte Orientale, Via Bovio 6, 28100 Novara, Italy.
Concettina La MottaDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.ORCID 0000-0002-0194-5431
Silvia GaravagliaDepartment of Scienze del Farmaco, University of Piemonte Orientale, Via Bovio 6, 28100 Novara, Italy.ORCID 0000-0001-8494-1729

Funding

Ministero della Salute PNRR-POC-2022-12376588 "Developing proprietary fluorescent probes targeting high grade gliomas into useful tools for oncosurgery and theranostic"
6 · The paper itself

Abstract

Aldehyde dehydrogenases of the subfamily 1A (ALDH1A) are enzymes necessary for the oxidation of all-

Indexed as

aldehyde dehydrogenaseALDH1A3cancersfluorescence-guided surgeryglioblastomamesotheliomaretinoic acid

Identifiers

PMID39001459
PMCPMC11240489

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.