Evidence map›Paper›PMID 39001398›Full record

ArticleCancers2024

Variances in the Expression Profile of Circadian Clock-Related Genes in Astrocytic Brain Tumors.

Rafał Staszkiewicz, Dawid Sobański, Wojciech Pulka, Dorian Gładysz, Marcin Gadzieliński, Damian Strojny, Beniamin Oskar Grabarek

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rafał StaszkiewiczCollegium Medicum, WSB University, 41-300 Dabrowa Gornicza, Poland.ORCID 0000-0002-0781-6534
Dawid SobańskiCollegium Medicum, WSB University, 41-300 Dabrowa Gornicza, Poland.ORCID 0000-0002-5525-6201
Wojciech PulkaDepartment of Neurosurgery, Neurotraumatology and Spinal Surgery, Regional Hospital in Elblag, 82-300 Elblag, Poland.
Dorian GładyszCollegium Medicum, WSB University, 41-300 Dabrowa Gornicza, Poland.
Marcin GadzielińskiCollegium Medicum, WSB University, 41-300 Dabrowa Gornicza, Poland.
Damian StrojnyCollegium Medicum, WSB University, 41-300 Dabrowa Gornicza, Poland.ORCID 0009-0007-2324-3039
Beniamin Oskar GrabarekCollegium Medicum, WSB University, 41-300 Dabrowa Gornicza, Poland.ORCID 0000-0003-1633-7145

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study explores the role of circadian clock genes in the progression of astrocytic tumors, a prevalent type of brain tumor. The aim was to assess the expression patterns of these genes in relation to the tumor grade. Using microarray analysis, qRT-PCR, and methylation-specific PCR, we examined gene expression, DNA methylation patterns, and microRNA interactions in tumor samples from 60 patients. Our results indicate that the expression of key circadian clock genes, such as clock circadian regulator

Indexed as

astrocytic tumorbiomarkersbrain neoplasmscircadian clocksenzyme-linked immunosorbent assaymessengermicroRNAsRNA

Identifiers

PMID39001398
PMCPMC11240661

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.