ArticleCancers2024
Scoring System for Predicting the Risk of Liver Cancer among Diabetes Patients: A Random Survival Forest-Guided Approach.
Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Interaction Patterns Among Risk Factors for Liver Cancer in Patients With Type 2 Diabetes in Primary Care: A Retrospective Cohort Study.Health science reports · 2026Article
- Risk factors for cancer among patients with type 2 diabetes: a retrospective cohort study.BMC cancer · 2025Article
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Authors and funding
7 authors.
Funding
Abstract
backgroundMost liver cancer scoring systems focus on patients with preexisting liver diseases such as chronic viral hepatitis or liver cirrhosis. Patients with diabetes are at higher risk of developing liver cancer than the general population. However, liver cancer scoring systems for patients in the absence of liver diseases or those with diabetes remain rare. This study aims to develop a risk scoring system for liver cancer prediction among diabetes patients and a sub-model among diabetes patients without cirrhosis/chronic viral hepatitis.
methodsA retrospective cohort study was performed using electronic health records of Hong Kong. Patients who received diabetes care in general outpatient clinics between 2010 and 2019 without cancer history were included and followed up until December 2019. The outcome was diagnosis of liver cancer during follow-up. A risk scoring system was developed by applying random survival forest in variable selection, and Cox regression in weight assignment.
resultsThe liver cancer incidence was 0.92 per 1000 person-years. Patients who developed liver cancer (
conclusionsThe proposed scoring system may provide a parsimonious score for liver cancer risk prediction among diabetes patients.
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