Evidence map›Paper›PMID 39001372›Full record

ArticleCancers2024

Multiparametric Ultrasound for Focal Testicular Pathology: A Ten-Year Retrospective Review.

Dean Y Huang, Majed Alsadiq, Gibran T Yusuf, Annamaria Deganello, Maria E Sellars, Paul S Sidhu

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Micro-ultrasound for prostate cancer.Nature reviews. Urology · 2026
    Review
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dean Y HuangDepartment of Clinical Radiology, King's College Hospital, London SE5 9RS, UK.ORCID 0000-0002-5637-6723
Majed AlsadiqDepartment of Imaging, The Royal London Hospital, London E1 1FR, UK.
Gibran T YusufDepartment of Clinical Radiology, King's College Hospital, London SE5 9RS, UK.
Annamaria DeganelloDepartment of Clinical Radiology, King's College Hospital, London SE5 9RS, UK.ORCID 0000-0003-4868-9604
Maria E SellarsDepartment of Clinical Radiology, King's College Hospital, London SE5 9RS, UK.
Paul S SidhuDepartment of Clinical Radiology, King's College Hospital, London SE5 9RS, UK.ORCID 0000-0003-1928-4077

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conventional ultrasonography (US), including greyscale imaging and colour Doppler US (CDUS), is pivotal for diagnosing scrotal pathologies, but it has limited specificity. Historically, solid focal testicular abnormalities often led to radical orchidectomy. This retrospective study evaluated the utilisation of contrast-enhanced ultrasound (CEUS) and strain elastography (SE) in investigating intratesticular focal abnormalities. A total of 124 cases were analysed. This study underscored the superior diagnostic capabilities of CEUS in detecting vascular enhancement in all malignant cases, even those with undetectable vascularity by CDUS. It also highlighted the potential of CEUS in identifying distinctive vascular patterns in benign vascular tumours. Definitive confirmation of benignity could be obtained when the absence of enhancement was demonstrated on CEUS. While SE alone offered no distinctive advantage in differentiating between benign and malignant pathologies, we demonstrated that incorporating a combination of CEUS and SE into the evaluation of focal testicular abnormalities could improve diagnostic performance metrics over conventional CDUS. Our findings underscore the role of advanced ultrasound techniques in enhancing the evaluation of focal testicular abnormalities in clinical practice and could aid a shift towards testis-sparing management strategies.

Indexed as

multiparametricorchiectomytesticular cancertestis-sparing surgeryultrasound

Identifiers

PMID39001372
PMCPMC11240835

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.