Evidence map›Paper›PMID 39001369›Full record

ArticleCancers2024

Comparing Two Targeted Biopsy Schemes for Detecting Clinically Significant Prostate Cancer in Magnetic Resonance Index Lesions: Two- to Four-Core versus Saturated Transperineal Targeted Biopsy.

Juan Morote, Nahuel Paesano, Natàlia Picola, Berta Miró, José M Abascal, Pol Servian, Enrique Trilla, Olga Méndez

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Juan MoroteDepartment of Urology, Vall d'Hebron University Hospital, 08035 Barcelona, Spain.ORCID 0000-0002-2168-323X
Nahuel PaesanoDepartment of Surgery, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain.ORCID 0000-0001-9278-5543
Natàlia PicolaDepartment of Urology, Bellvitge University Hospital, Hospitalet de Llobregat, 08907 Barcelona, Spain.
Berta MiróStatistics Unit, Vall d'Hebron Research Institute, 08035 Barcelona, Spain.
José M AbascalDepartment of Urology, Parc de Salut Mar, 08003 Barcelona, Spain.
Pol ServianDepartment of Urology, Hospital Germans Trias I Pujol, 08916 Badalona, Spain.
Enrique TrillaDepartment of Urology, Vall d'Hebron University Hospital, 08035 Barcelona, Spain.
Olga MéndezResearch Group in Urology, Vall d'Hebron Research Institute, 08035 Barcelona, Spain.

Funding

Instituto de Salut Carlos III (SP) PI20/01666Ministerio de Asuntos Económicos y Transformación Digital MIA.2021.M02.0005
6 · The paper itself

Abstract

Since the optimal scheme for targeted biopsies of magnetic resonance imaging (MRI) suspicious lesions remains unclear, we compare the efficacy of two schemes for these index lesions. A prospective trial was conducted in 1161 men with Prostate Imaging Reporting and Data System v 2.1 3-5 undergoing targeted and 12-core systematic biopsy in four centers between 2021 and 2023. Two- to four-core MRI-transrectal ultrasound fusion-targeted biopsies via the transperineal route were conducted in 900 men in three centers, while a mapping per 0.5 mm core method (saturated scheme) was employed in 261 men biopsied in another center. A propensity-matched 261 paired cases were selected for avoiding confounders other than the targeted biopsy scheme. CsPCa (grade group ≥ 2) was identified in 125 index lesions (41.1%) when the two- to four-core scheme was employed, while in 187 (71.9%) when the saturated biopsy (

Indexed as

index lesionnumber of coresprostate cancertargeted biopsy

Identifiers

PMID39001369
PMCPMC11240532

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.