Evidence map›Paper›PMID 39001314›Full record

ArticleDiagnostics (Basel, Switzerland)2024

Real Implication of Fertility-Sparing Surgery for Ovarian Cancer: Reproductive Outcomes.

Marta Heras, Maria Alonso-Espias, Octavio Arencibia, Lucas Minig, Lola Marti, Maria Dolores Diestro, Juan Cespedes, Isabel Niguez, Blanca Gil-Ibañez, Berta Diaz-Feijoo and 10 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Marta HerasGynecology Department, Hospital Universitario Santa Cristina, 28009 Madrid, Spain.ORCID 0000-0002-5095-9143
Maria Alonso-EspiasGynecologic Oncology Unit, La Paz University Hospital, 28046 Madrid, Spain.
Octavio ArencibiaGynecology Department, Hospital Universitario Materno Infantil, 06010 Las Palmas de Gran Canaria, Spain.ORCID 0000-0001-7352-8920
Lucas MinigGynecology Department, IMED Hospitales, 46100 Valencia, Spain.
Lola MartiGynecology Department, Hospital Universitario Bellvitge, 08907 Barcelona, Spain.
Maria Dolores DiestroGynecologic Oncology Unit, La Paz University Hospital, 28046 Madrid, Spain.
Juan CespedesGynecology Department, Hospital Universitario de Donostia, 20014 San Sebastian, Spain.ORCID 0000-0002-5097-8635
Isabel NiguezGynecology Department, Hospital Virgen de la Arrixaca, 30120 Murcia, Spain.ORCID 0000-0001-7264-6802
Blanca Gil-IbañezGynecology Department, Hospital Universitario 12 de Octubre, 28041 Madrid, Spain.ORCID 0000-0002-0361-8741
Berta Diaz-FeijooInstitute Clinic of Gynecology, Obstetrics and Neotatology, Hospital Clinic de Barcelona, 08007 Barcelona, Spain.ORCID 0000-0002-6451-1817
Antoni LluecaGynecology Department, Hospital de Castellón, 12004 Castellón, Spain.ORCID 0000-0003-3723-8795
Claudia RosadoGynecology Department, Hospital de Mataró, 08304 Barcelona, Spain.
Sara IacoponiGynecology Department, Hospital Quirón Madrid, 28223 Madrid, Spain.ORCID 0000-0002-0314-1752
Carlos Lopez de la ManzanaraGynecology Department, Hospital General Universitario de Ciudad Real, 13005 Ciudad Real, Spain.
Sara MoralesGynecology Department, Hospital Universitario Infanta Leonor, 28031 Madrid, Spain.
Maria Jose Fernandez-GalgueraGynecology Department, Complejo Asistencial de Zamora, 49022 Zamora, Spain.
Ana CanoGynecology Department, Hospital Universitario Fundación Alcorcón, 28922 Madrid, Spain.ORCID 0000-0002-3865-7660
Mikel GorostidiGynecology Department, Hospital Universitario de Donostia, 20014 San Sebastian, Spain.ORCID 0000-0001-5150-2797
Ignacio ZapardielGynecologic Oncology Unit, La Paz University Hospital, 28046 Madrid, Spain.ORCID 0000-0002-9175-7767
YOC-Care Collaborative Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundto prove the effectivity of fertility-sparing procedures in early-stage ovarian cancer by assessing pregnancy rates and obstetrical outcomes.

methodswe performed a retrospective multicenter study among 55 Spanish hospitals, collecting patients from 18 to 40 years old with diagnosis of early-stage ovarian cancer, epithelial (EOC) or non-epithelial (non-EOC), from January 2010 to December 2019. Data on the use of assisted reproductive techniques, pregnancy attempts and obstetrical outcomes were collected.

resultsa total of 150 patients met inclusion criteria, 70 (46.6%) EOC and 80 (53.4%) non-EOC. Pregnancy attempts were reported in 51 (34%) patients, with 42 (28%) patients carrying the pregnancy to term. Among them, 30 (71.4%) underwent surgery alone and 12 (28.6%) had additional postoperative chemotherapy. A total of 32 (76.1% patients) had spontaneous pregnancies and 10 (23.9%) required in vitro fertilization. There was only one (2.4%) complication reported. Vaginal delivery was reported in twenty-nine (69%) patients and cesarean section in five (11.9%) patients.

conclusionsfertility-sparing management for ovarian cancer seems to be an option with proven good pregnancy rates and low complications. The selection of patients must consider strict criteria in order to maintain a good prognosis.

Indexed as

fertilityovarian cancerpregnancy

Identifiers

PMID39001314
PMCPMC11241223

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.