Evidence map›Paper›PMID 39000745›Full record

ArticlePolymers2024

Enhanced Antibacterial Activity of Vancomycin Loaded on Functionalized Polyketones.

Rachele Rampazzo, Andrea Vavasori, Lucio Ronchin, Pietro Riello, Martina Marchiori, Gloria Saorin, Valentina Beghetto

Abstract read
In one paragraph

Article in Polymers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rachele RampazzoDepartment of Molecular Sciences and Nanosystems, University Ca' Foscari of Venice, Via Torino5 155, 30172 Venice, Italy.
Andrea VavasoriDepartment of Molecular Sciences and Nanosystems, University Ca' Foscari of Venice, Via Torino5 155, 30172 Venice, Italy.ORCID 0000-0002-3823-9952
Lucio RonchinDepartment of Molecular Sciences and Nanosystems, University Ca' Foscari of Venice, Via Torino5 155, 30172 Venice, Italy.
Pietro RielloDepartment of Molecular Sciences and Nanosystems, University Ca' Foscari of Venice, Via Torino5 155, 30172 Venice, Italy.
Martina MarchioriDepartment of Molecular Sciences and Nanosystems, University Ca' Foscari of Venice, Via Torino5 155, 30172 Venice, Italy.
Gloria SaorinDepartment of Molecular Sciences and Nanosystems, University Ca' Foscari of Venice, Via Torino5 155, 30172 Venice, Italy.ORCID 0000-0002-0710-692X
Valentina BeghettoDepartment of Molecular Sciences and Nanosystems, University Ca' Foscari of Venice, Via Torino5 155, 30172 Venice, Italy.ORCID 0000-0001-8799-210X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Today, polymeric drug delivery systems (DDS) appear as an interesting solution against bacterial resistance, having great advantages such as low toxicity, biocompatibility, and biodegradability. In this work, two polyketones (PK) have been post-functionalized with sodium taurinate (PKT) or potassium sulfanilate (PKSK) and employed as carriers for Vancomycin against bacterial infections. Modified PKs were easily prepared by the Paal-Knorr reaction and loaded with Vancomycin at a variable pH. All polymers were characterized by FT-IR, DSC, TGA, SEM, and elemental analysis. Antimicrobial activity was tested against Gram-positive

Indexed as

antibioticsdrug deliveryPaal–KnorrpolyketoneVancomycin

Identifiers

PMID39000745
PMCPMC11244503

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.