Evidence map›Paper›PMID 39000666›Full record

ArticlePolymers2024

Oral Films Printed with Green Propolis Ethanolic Extract.

Leandro Neodini Remedio, Vitor Augusto Dos Santos Garcia, Arina Lazaro Rochetti, Andresa Aparecida Berretta, Julieta Adriana Ferreira, Heidge Fukumasu, Fernanda Maria Vanin, Cristiana Maria Pedroso Yoshida, Rosemary Aparecida de Carvalho

Abstract read
In one paragraph

Article in Polymers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Leandro Neodini RemedioFaculty of Animal Science and Food Engineering, USP-University of São Paulo, Av. Duque de Caxias Norte 225, Pirassununga 13635-900, SP, Brazil.
Vitor Augusto Dos Santos GarciaFaculty of Agricultural Sciences, UNESP-São Paulo State University, José Barbosa de Barros 1780, Botucatu 18610-034, SP, Brazil.ORCID 0000-0002-7011-616X
Arina Lazaro RochettiFaculty of Animal Science and Food Engineering, USP-University of São Paulo, Av. Duque de Caxias Norte 225, Pirassununga 13635-900, SP, Brazil.
Andresa Aparecida BerrettaResearch, Development & Innovation Department, Apis Flora Industrial e Comercial Ltda, Rua Triunfo 945, Ribeirão Preto 14020-670, SP, Brazil.ORCID 0000-0001-5719-1301
Julieta Adriana FerreiraFHO-Hermínio Ometto Foundation, Av. Doutor Maximiliano Baruto 500, Araras 13607-339, SP, Brazil.
Heidge FukumasuFaculty of Animal Science and Food Engineering, USP-University of São Paulo, Av. Duque de Caxias Norte 225, Pirassununga 13635-900, SP, Brazil.ORCID 0000-0002-3265-5090
Fernanda Maria VaninFaculty of Animal Science and Food Engineering, USP-University of São Paulo, Av. Duque de Caxias Norte 225, Pirassununga 13635-900, SP, Brazil.ORCID 0000-0001-5583-7092
Cristiana Maria Pedroso YoshidaInstitute of Environmental, Chemical and Pharmaceutical Sciences, UNIFESP-Federal University of São Paulo, Rua São Nicolau 210, Diadema 09913-030, SP, Brazil.ORCID 0000-0003-3068-8187
Rosemary Aparecida de CarvalhoFaculty of Animal Science and Food Engineering, USP-University of São Paulo, Av. Duque de Caxias Norte 225, Pirassununga 13635-900, SP, Brazil.ORCID 0000-0002-4284-0994

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 001National Council for Scientific and Technological Development 424106/2018-3
6 · The paper itself

Abstract

Oral film (OF) research has intensified due to the effortless administration and advantages related to absorption in systemic circulation. Chitosan is one of the polymers widely used in the production of OFs; however, studies evaluating the maintenance of the active principles' activity are incipient. Propolis has been widely used as an active compound due to its different actions. Printing techniques to incorporate propolis in OFs prove to be efficient. The objective of the present study is to develop and characterize oral films based on chitosan and propolis using printing techniques and to evaluate the main activities of the extract incorporated into the polymeric matrix. The OFs were characterized in relation to the structure using scanning and atomic force electron microscopy; the mechanical properties, disintegration time, wettability, and stability of antioxidant activity were evaluated. The ethanolic extract of green propolis (GPEE) concentration influenced the properties of the OFs. The stability (phenolic compounds and antioxidant activity) was reduced in the first 20 days, and after this period, it remained constant.

Indexed as

printing layersroughnessstabilitytape casting

Identifiers

PMID39000666
PMCPMC11243841

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.