ArticlePolymers2024
Enhancing Wound Recovery: A Self-Gelling Powder for Improved Hemostasis and Healing.
Article in Polymers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Influence of carboxymethyl cellulose and calcium-crosslinked CMC coating of 3D-Printed hydroxyapatite scaffolds on the early hemostatic performance and osteoblastic compatibility.Frontiers in bioengineering and biotechnology · 2026Article
- Current Challenges in Hemostasis and Advances in Particle-Assisted Styptic Devices.Advanced healthcare materials · 2026Review
- Evaluation of the hemostatic efficacy and safety of an absorbable hemostatic powder based on a porcine intracranial hemorrhage model.Frontiers in bioengineering and biotechnology · 2026Article
- Chlorocatechol-functionalized gelatin nanoparticles as a hemostatic agent with antimicrobial properties.Acta biomaterialia · 2025Article
- Recent Trends in the Application of Cellulose-Based Hemostatic and Wound Healing Dressings.Journal of functional biomaterials · 2025Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A novel self-gelatinizing powder was designed to accelerate wound healing through enhanced hemostasis and tissue recovery. Significantly, this research addresses the critical need for innovative wound management solutions by presenting a novel approach. Carboxymethylcellulose calcium (CMC-Ca) was synthesized using an ion exchange method, and lysine (Lys) was integrated through physical mixing to augment the material's functional characteristics. The prepared powder underwent comprehensive evaluation for its self-gelling capacity, gelation time, adhesion, swelling rate, coagulation efficiency, hemostatic effectiveness, and wound healing promotion. Results indicate that the self-gelatinizing powder exhibited remarkable water absorption capabilities, absorbing liquid up to 30 times its weight and achieving rapid coagulation within 3 min. The inclusion of Lys notably enhanced the powder's gel-forming properties. The gelation time was determined to be within 4 s using a rotational rheometer, with the powder rapidly forming a stable gel on the skin surface. Furthermore, in a mouse skin injury model, near-complete skin recovery was observed within 14 days, underscoring the powder's impressive self-healing attributes and promising application prospects in wound management.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.