Evidence map›Paper›PMID 39000558›Full record

ArticleInternational journal of molecular sciences2024

Differential Impairment Mechanism of Sperm Production via Induction of miR-34c-Activated Apoptosis and Spermatogenesis Pathway in Diet-Induced Obesity and Resistant Mice and GC-1 Spg Cells.

Mujiao Li, Qing Zhao, Siyu Wang, Yangyang Song, Lingling Zhai, Jian Zhao

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Sperm abnormality: Differential expression of microRNAs.Journal of assisted reproduction and genetics · 2025
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mujiao LiDepartment of Pharmacology, Shenyang Pharmaceutical University, No. 103, Wenhua Rd., Shenhe District, Shenyang 110016, China.
Qing ZhaoDepartment of Pharmacology, Shenyang Pharmaceutical University, No. 103, Wenhua Rd., Shenhe District, Shenyang 110016, China.
Siyu WangDepartment of Pharmacology, Shenyang Pharmaceutical University, No. 103, Wenhua Rd., Shenhe District, Shenyang 110016, China.
Yangyang SongDepartment of Pharmacology, Shenyang Pharmaceutical University, No. 103, Wenhua Rd., Shenhe District, Shenyang 110016, China.
Lingling ZhaiDepartment of Maternal, Child and Adolescent Health, School of Public Health, China Medical University, Shenyang 110122, China.
Jian ZhaoDepartment of Pharmacology, Shenyang Pharmaceutical University, No. 103, Wenhua Rd., Shenhe District, Shenyang 110016, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Male reproductive dysfunction is a clinical disease, with a large number of cases being idiopathic. Reproductive disorders have been found in obese (diet-induced obesity and diet-induced obesity-resistant) mice, but the mechanism behind the male reproductive dysfunction between them may be different. The purpose of this study was to explore the possible role and mechanism of

Indexed as

ApoptosisDiet, High-FatMice, Inbred C57BLMicroRNAsObesitySpermatogenesisSpermatozoaAnimalsCell LineMaleMiceMicroRNAsMIRN34a microRNA, mouseapoptosishigh-diet-induced obesityhigh-diet-induced obesity resistantmale reproductionspermatogenesis

Identifiers

PMID39000558
PMCPMC11242685

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.