Evidence map›Paper›PMID 39000496›Full record

ArticleInternational journal of molecular sciences2024

Interactions with DNA Models of the Oxaliplatin Analog (

Alessandra Barbanente, Paride Papadia, Anna Maria Di Cosola, Concetta Pacifico, Giovanni Natile, James D Hoeschele, Nicola Margiotta

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alessandra BarbanenteDipartimento di Chimica, Università degli Studi di Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy.ORCID 0000-0002-9001-8719
Paride PapadiaDepartment of Biological and Environmental Sciences and Technologies (DiSTeBA), University of Salento, 73100 Lecce, Italy.ORCID 0000-0001-9611-3824
Anna Maria Di CosolaDipartimento di Chimica, Università degli Studi di Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy.
Concetta PacificoDipartimento di Chimica, Università degli Studi di Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy.
Giovanni NatileDipartimento di Chimica, Università degli Studi di Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy.ORCID 0000-0002-1790-6365
James D HoescheleDepartment of Chemistry, Eastern Michigan University, Ypsilanti, MI 48197, USA.
Nicola MargiottaDipartimento di Chimica, Università degli Studi di Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy.ORCID 0000-0003-4034-875X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is generally accepted that adjacent guanine residues in DNA are the primary target for platinum antitumor drugs and that differences in the conformations of the Pt-DNA adducts can play a role in their antitumor activity. In this study, we investigated the effect of the carrier ligand

Indexed as

DNADNA AdductsOxaliplatinAntineoplastic AgentsLigandsModels, MolecularNucleic Acid ConformationOrganoplatinum CompoundsAntineoplastic AgentsDNADNA AdductsLigandsOrganoplatinum CompoundsOxaliplatinantitumor compoundscis-1,3-diaminocyclohexanecisplatinDNA adductsoxaliplatin

Identifiers

PMID39000496
PMCPMC11242235

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.