Evidence map›Paper›PMID 39000467›Full record

ArticleInternational journal of molecular sciences2024

ERK/CREB and p38 MAPK/MMP14 Signaling Pathway Influences Spermatogenesis through Regulating the Expression of Junctional Proteins in

Hong-Yu Qi, Zhan Zhao, Bang-Hong Wei, Zhen-Fang Li, Fu-Qing Tan, Wan-Xi Yang

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hong-Yu QiThe Sperm Laboratory, College of Life Sciences, Zhejiang University, Hangzhou 310058, China.
Zhan ZhaoThe Sperm Laboratory, College of Life Sciences, Zhejiang University, Hangzhou 310058, China.
Bang-Hong WeiThe Sperm Laboratory, College of Life Sciences, Zhejiang University, Hangzhou 310058, China.
Zhen-Fang LiThe Sperm Laboratory, College of Life Sciences, Zhejiang University, Hangzhou 310058, China.
Fu-Qing TanSchool of Medicine, Zhejiang University, Hangzhou 310003, China.
Wan-Xi YangThe Sperm Laboratory, College of Life Sciences, Zhejiang University, Hangzhou 310058, China.

Funding

National Natural Science Foundation of China 32072954National Natural Science Foundation of China 32270555
6 · The paper itself

Abstract

The hemolymph-testis barrier (HTB) is a reproduction barrier in Crustacea, guaranteeing the safe and smooth process of spermatogenesis, which is similar to the blood-testis barrier (BTB) in mammals. The MAPK signaling pathway plays an essential role in spermatogenesis and maintenance of the BTB. However, only a few studies have focused on the influence of MAPK on crustacean reproduction. In the present study, we knocked down and inhibited MAPK in

Indexed as

BrachyuraCyclic AMP Response Element-Binding ProteinMAP Kinase Signaling Systemp38 Mitogen-Activated Protein KinasesSpermatogenesisTestisAnimalsBlood-Testis BarrierMaleSignal TransductionCyclic AMP Response Element-Binding Proteinp38 Mitogen-Activated Protein KinasesEriocheir sinensishemolymph–testis barrierintercellular junctionMAPKspermatogenesis

Identifiers

PMID39000467
PMCPMC11242087

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.