Evidence map›Paper›PMID 39000427›Full record

ArticleInternational journal of molecular sciences2024

Polysaccharides from

Bo-Yu Hou, Ming-Hsuan Wu, Hui-Yu Hsu, Yi-Chun Lin, Ding-I Yang

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bo-Yu HouInstitute of Brain Science, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.
Ming-Hsuan WuInstitute of Brain Science, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.ORCID 0009-0007-0981-1335
Hui-Yu HsuMynature Biotech Inc., Yilan 260021, Taiwan.
Yi-Chun LinDepartment of Neurology, Taipei City Hospital Renai Branch, Taipei 106243, Taiwan.
Ding-I YangInstitute of Brain Science, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.ORCID 0000-0001-5544-7561

Funding

Department of Health in Taipei City Government in Taiwan 10801-62-003; 11001-62-038; 11101-62-006Ministry of Education (MOE) in Taiwan 113W032101National Science and Technology Council, Taiwan MOST 107-2314-B-010-020-MY3; MOST 109-2314-B-010-038-MY3; NSTC 112-2320-B-A49-029-MY3
6 · The paper itself

Abstract

The amyloid-beta peptide (Aβ) is the neurotoxic component in senile plaques of Alzheimer's disease (AD) brains. Previously we have reported that Aβ toxicity is mediated by the induction of sonic hedgehog (SHH) to trigger cell cycle re-entry (CCR) and apoptosis in post-mitotic neurons.

Indexed as

Amyloid beta-PeptidesApoptosisCell CycleHedgehog ProteinsNeuronsPolysaccharidesAnimalsCell SurvivalNeuroprotective AgentsPeptide FragmentsRatsAmyloid beta-Peptidesamyloid beta-protein (25-35)Hedgehog ProteinsNeuroprotective AgentsPeptide FragmentsPolysaccharidesShh protein, rat5-bromo-2′-deoxyuridine (BrdU)Alzheimer’s diseasecaspase-3cyclin D1histone H3mitochondriaproliferating cell nuclear antigen (PCNA)

Identifiers

PMID39000427
PMCPMC11242684

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.