Evidence map›Paper›PMID 39000391›Full record

ArticleInternational journal of molecular sciences2024

Long-Term Proton Pump Inhibitor-Acid Suppressive Treatment Can Cause Vitamin B

Tetsuhide Ito, Irene Ramos-Alvarez, Robert T Jensen

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tetsuhide ItoNeuroendocrine Tumor Centra, Fukuoka Sanno Hospital, International University of Health and Welfare, 3-6-45 Momochihama, Sawara-Ku, Fukuoka 814-0001, Japan.
Irene Ramos-AlvarezDigestive Diseases Branch, NIDDK, NIH, Bethesda, MD 20892-1804, USA.
Robert T JensenDigestive Diseases Branch, NIDDK, NIH, Bethesda, MD 20892-1804, USA.

Funding

Diagnosis, Natural History, Management,tumor biology of Gastrinomas/PETs/Neuroendocrine tumorsZIADK053200 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI JENSEN, ROBERT · 2009 to 2025
$4.3M
N IH intramural funds from NIDDK NIDDK #DK053200-26
6 · The paper itself

Abstract

Whether the long-term treatment of patients with proton pump inhibitors (PPIs) with different diseases [GERD, Zollinger-Ellison syndrome (ZES), etc.] can result in vitamin B

Indexed as

Proton Pump InhibitorsVitamin B 12Vitamin B 12 DeficiencyZollinger-Ellison SyndromeAdultAgedFemaleHomocysteineHumansMaleMethylmalonic AcidMiddle AgedHomocysteineMethylmalonic AcidProton Pump InhibitorsVitamin B 12acid hypersecretiongastrinomasmethylmalonic acidneuroendocrine tumorPPItotal homocysteinevitamin B12 deficiencyZollinger–Ellison syndrome

Identifiers

PMID39000391
PMCPMC11242121

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.