Evidence map›Paper›PMID 39000373›Full record

ReviewInternational journal of molecular sciences2024

Inflammatory and Immune Mechanisms for Atherosclerotic Cardiovascular Disease in HIV.

Laura Hmiel, Suyu Zhang, Laventa M Obare, Marcela Araujo de Oliveira Santana, Celestine N Wanjalla, Boghuma K Titanji, Corrilynn O Hileman, Shashwatee Bagchi

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Immuno-cell metabolic changes in HIV-1 infection.Infectious diseases & immunity · 2025
    Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Risk of Cardiovascular Disease Among People Living With HIV With Immunological Nonresponse.Journal of the International Association of Providers of AIDS Care
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Laura HmielDepartment of Medicine, Division of Infectious Disease, MetroHealth Medical Center and Case Western Reserve University, Cleveland, OH 44109, USA.
Suyu ZhangDepartment of Medicine, Emory University, Atlanta, GA 30322, USA.
Laventa M ObareDivision of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Marcela Araujo de Oliveira SantanaDepartment of Medicine, Washington University in St. Louis, St. Louis, MO 63110, USA.
Celestine N WanjallaDivision of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Boghuma K TitanjiDivision of Infectious Diseases, Emory University, Atlanta, GA 30322, USA.
Corrilynn O HilemanDepartment of Medicine, Division of Infectious Disease, MetroHealth Medical Center and Case Western Reserve University, Cleveland, OH 44109, USA.
Shashwatee BagchiDivision of Infectious Diseases, Washington University in St. Louis, St. Louis, MO 63110, USA.ORCID 0000-0002-8043-8605

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerotic vascular disease disproportionately affects persons living with HIV (PLWH) compared to those without. The reasons for the excess risk include dysregulated immune response and inflammation related to HIV infection itself, comorbid conditions, and co-infections. Here, we review an updated understanding of immune and inflammatory pathways underlying atherosclerosis in PLWH, including effects of viral products, soluble mediators and chemokines, innate and adaptive immune cells, and important co-infections. We also present potential therapeutic targets which may reduce cardiovascular risk in PLWH.

Indexed as

AtherosclerosisHIV InfectionsInflammationAnimalsCardiovascular DiseasesHumansImmunity, Innateadaptive immune systematherosclerosiscardiovascular diseaseHIVimmune systeminflammationinnate immune systemmechanismsmonocytes/macrophagesT lymphocytes

Identifiers

PMID39000373
PMCPMC11242562

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.