Evidence map›Paper›PMID 39000344›Full record

ArticleInternational journal of molecular sciences2024

ProPept-MT: A Multi-Task Learning Model for Peptide Feature Prediction.

Guoqiang He, Qingzu He, Jinyan Cheng, Rongwen Yu, Jianwei Shuai, Yi Cao

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Guoqiang HePostgraduate Training Base Alliance, Wenzhou Medical University, Wenzhou 325000, China.
Qingzu HeDepartment of Physics, and Fujian Provincial Key Laboratory for Soft Functional Materials Research, Xiamen University, Xiamen 361005, China.
Jinyan ChengWenzhou Institute, University of Chinese Academy of Sciences, Wenzhou 325000, China.
Rongwen YuWenzhou Institute, University of Chinese Academy of Sciences, Wenzhou 325000, China.
Jianwei ShuaiWenzhou Institute, University of Chinese Academy of Sciences, Wenzhou 325000, China.
Yi CaoPostgraduate Training Base Alliance, Wenzhou Medical University, Wenzhou 325000, China.ORCID 0000-0003-1493-7868

Funding

Ministry of Science and Technology of the People's Republic of China STI2030-Major Projects2021ZD0201900National Natural Science Foundation of China 12090052
6 · The paper itself

Abstract

In the realm of quantitative proteomics, data-independent acquisition (DIA) has emerged as a promising approach, offering enhanced reproducibility and quantitative accuracy compared to traditional data-dependent acquisition (DDA) methods. However, the analysis of DIA data is currently hindered by its reliance on project-specific spectral libraries derived from DDA analyses, which not only limits proteome coverage but also proves to be a time-intensive process. To overcome these challenges, we propose ProPept-MT, a novel deep learning-based multi-task prediction model designed to accurately forecast key features such as retention time (RT), ion intensity, and ion mobility (IM). Leveraging advanced techniques such as multi-head attention and BiLSTM for feature extraction, coupled with Nash-MTL for gradient coordination, ProPept-MT demonstrates superior prediction performance. Integrating ion mobility alongside RT, mass-to-charge ratio (

Indexed as

PeptidesProteomicsDeep LearningHumansProteomeReproducibility of ResultsPeptidesProteomedeep learningion intensityion mobilitymulti-task learningproteomicsretention time

Identifiers

PMID39000344
PMCPMC11241495

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.