Evidence map›Paper›PMID 39000309›Full record

ArticleInternational journal of molecular sciences2024

Mannan-Binding Lectin Is Associated with Inflammation and Kidney Damage in a Mouse Model of Type 2 Diabetes.

Gry H Dørflinger, Charlotte B Holt, Steffen Thiel, Jesper N Bech, Jakob A Østergaard, Mette Bjerre

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. IJMS Special Issue-Molecular Mechanisms of Diabetic Kidney Disease 2.0.International journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gry H DørflingerMedical/Steno Aarhus Research Laboratory, Department of Clinical Medicine, Aarhus University, 8200 Aarhus, Denmark.
Charlotte B HoltMedical/Steno Aarhus Research Laboratory, Department of Clinical Medicine, Aarhus University, 8200 Aarhus, Denmark.ORCID 0000-0002-7503-5879
Steffen ThielDepartment of Biomedicine, Aarhus University, 8200 Aarhus, Denmark.ORCID 0000-0002-4817-155X
Jesper N BechDepartment of Internal Medicine, Regional Hospital Gødstrup, 7400 Herning, Denmark.ORCID 0000-0002-0605-1277
Jakob A ØstergaardDepartment of Endocrinology and Internal Medicine, Aarhus University Hospital, 8200 Aarhus, Denmark.ORCID 0000-0002-9877-5327
Mette BjerreMedical/Steno Aarhus Research Laboratory, Department of Clinical Medicine, Aarhus University, 8200 Aarhus, Denmark.

Funding

A. P. Møller Foundation for Advancement of Medical Science 20-L-0224Danmarks Frie Forskningsfond DFF 7016-000115
6 · The paper itself

Abstract

Autoreactivity of the complement system may escalate the development of diabetic nephropathy. We used the BTBR OB mouse model of type 2 diabetes to investigate the role of the complement factor mannan-binding lectin (MBL) in diabetic nephropathy. Female BTBR OB mice (

Indexed as

Diabetes Mellitus, Type 2Diabetic NephropathiesDisease Models, AnimalInflammationMannose-Binding LectinAnimalsDiabetes Mellitus, ExperimentalFemaleHumansKidneyMiceMannose-Binding LectinBTBR micecomplementdiabetic nephropathyinflammationMBLOB

Identifiers

PMID39000309
PMCPMC11241296

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.