Evidence map›Paper›PMID 39000289›Full record

ArticleInternational journal of molecular sciences2024

Ambient Particulate Matter Induces In Vitro Toxicity to Intestinal Epithelial Cells without Exacerbating Acute Colitis Induced by Dextran Sodium Sulfate or 2,4,6-Trinitrobenzenesulfonic Acid.

Candace Chang, Allen Louie, Yi Zhou, Rajat Gupta, Fengting Liang, Georgina Xanthou, Jason Ereso, Carolina Koletic, Julianne Ching Yang, Farzaneh Sedighian and 10 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Candace ChangVatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0002-1568-7648
Allen LouieDivision of Cardiology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0003-0526-1026
Yi ZhouVatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0002-9912-581X
Rajat GuptaDivision of Cardiology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0003-2887-1935
Fengting LiangVatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.
Georgina XanthouVatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0001-7944-2343
Jason EresoVatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.ORCID 0009-0003-4773-4925
Carolina KoleticVatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.
Julianne Ching YangVatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0001-5898-7221
Farzaneh SedighianVatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.
Venu LagishettyVatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0001-6500-8255
Nerea Arias-JayoVatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.
Abdulmalik AltuwayjiriUSC Viterbi School of Engineering, University of Southern California, Los Angeles, CA 90089, USA.ORCID 0000-0003-1540-3198
Ramin TohidiUSC Viterbi School of Engineering, University of Southern California, Los Angeles, CA 90089, USA.ORCID 0000-0001-7957-4223
Mohamad NavabDivision of Cardiology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.
Srinivasa Tadiparthi ReddyDivision of Cardiology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0003-2959-9531
Constantinos SioutasUSC Viterbi School of Engineering, University of Southern California, Los Angeles, CA 90089, USA.ORCID 0000-0001-5146-0857
Tzung HsiaiDivision of Cardiology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.
Jesus A AraujoDivision of Cardiology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.
Jonathan P JacobsVatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0003-4698-0254

Funding

Training in Molecular ToxicologyT32ES015457 · NIEHS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ALLARD, PATRICK, HANKINSON, OLIVER NMN · 2008 to 2025
$4.0M
Dissecting the Role of Arachidonic Acid Metabolic Pathways Involved in Resolution Versus Progression of PM-Induced Cardiometabolic ToxicityR01ES033703 · NIEHS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Jesus Antonio Araujo · 2022 to 2026
$3.3M
Role of Intestinal Microbiota in Dyslipidemia and Atherosclerosis Induced by Ambient Ultrafine ParticlesR01ES029395 · NIEHS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARAUJO, JESUS ANTONIO, HSIAI, TZUNG K · 2018 to 2022
$2.2M
Interplay Between Macrophages, Lipid Oxidation and the Nrf2/HO-1 Axis in the Cardiometabolic Toxicity Induced by Ultrafine ParticlesR01ES032806 · NIEHS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARAUJO, JESUS ANTONIO · 2021 to 2025
$2.0M
NIH HHS ES029395-02S1NIH HHS R01 ES029395NIH HHS R01 ES032806NIH HHS R01 ES033703UCLA NIEHS Training Grant in Molecular Toxicology T32-ES015457Veterans Administration Greater Los Angeles Healthcare System CDA2 IK2CX001717
6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) is an immunologically complex disorder involving genetic, microbial, and environmental risk factors. Its global burden has continued to rise since industrialization, with epidemiological studies suggesting that ambient particulate matter (PM) in air pollution could be a contributing factor. Prior animal studies have shown that oral PM

Indexed as

ColitisDextran SulfateMice, Inbred C57BLParticulate MatterTrinitrobenzenesulfonic AcidAnimalsCaco-2 CellsDisease Models, AnimalEpithelial CellsHumansIntestinal MucosaMaleMiceParticle SizeDextran SulfateParticulate MatterTrinitrobenzenesulfonic Acidcolitisinflammationinhalationparticulate matterultrafine particles

Identifiers

PMID39000289
PMCPMC11241079

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.