ReviewInternational journal of molecular sciences2024
Follicular Fluid and Blood Monitorization of Infertility Biomarkers in Women with Endometriosis.
Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Associations Between Follicular Fluid Biomarkers and IVF/ICSI Outcomes in Normo-Ovulatory Women-A Systematic Review.Biomolecules · 2025Pooled it
- Aberrant mitochondria in endometriosis: From pathogenic mechanisms to therapeutic opportunities.iScience · 2026Review
- Lactate metabolism and lactylation in female reproductive diseases: From metabolic rewiring to biomarkers and translational therapeutics.Clinical and translational medicine · 2026Review
- Modulatory Effects of Antioxidant Supplementation on Serum Oxidative Stress Biomarkers MDA and T-AOC in Females with Unexplained Infertility.Antioxidants (Basel, Switzerland) · 2026Article
- Association between circulating metabolites and endometriosis: a bidirectional two-sample Mendelian randomization study.Obstetrics & gynecology science · 2026Article
- Immunometabolic-uterine-ovarian interactions and flushing therapy in dairy cows: a narrative review.Veterinary world · 2026Review
- The Potential of Volatilomics as Female Fertilization Biomarkers in Assisted Reproductive Techniques.Biomedicines · 2026Article
- Transvaginal ultrasound combined with serum anti-Müllerian hormone, follicle-stimulating hormone, and luteinizing hormone in the evaluation of ovarian reserve function in infertile patients.American journal of translational research · 2026Article
- The Influence of Ovarian-Derived Extracellular Vesicles in Reproduction.Advances in anatomy, embryology, and cell biology · 2026Review
- Modeling Endometriosis in Mice and Pharmacological Activity of the Drug Endoferin.Bulletin of experimental biology and medicine · 2025Article
- Uterine artery S/D ratio and serum CA125 as predictors of early pregnancy loss in women with ovarian endometriomas: a retrospective case-control study.BMC pregnancy and childbirth · 2025Article
- Follicular Fluid Amino Acid Alterations in Endometriosis: Evidence for Oxidative Stress and Metabolic Dysregulation.Biomedicines · 2025Article
- Article
- Non-targeted metabolomic analysis of follicular fluid in infertile individuals with poor ovarian response.Frontiers in endocrinology · 2025Article
- Association Between the C-Reactive Protein-Albumin-Lymphocyte Index and Endometriosis: Insights from the 1999-2006 National Health and Nutrition Examination Survey.International journal of women's health · 2025Article
- Causal Effects of Endometriosis Stages on Adverse Pregnancy and Perinatal Outcomes: A Mendelian Randomization Study.International journal of women's health · 2025Article
- Autophagy and Female Fertility: Mechanisms, Clinical Implications, and Emerging Therapies.Cells · 2024Review
- Metabolomic Analysis of Follicular Fluid in Normal-Weight Patients with Polycystic Ovary Syndrome.Biomedicines · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Infertility is recognized globally as a social disease and a growing medical condition, posing a significant challenge to modern reproductive health. Endometriosis, the third-most frequent gynecologic disorder, is one of the most common and intricate conditions that can lead to female infertility. Despite extensive research, the etiology, malignant transformation, and biological therapy of endometriosis remain unknown. Blood and follicular fluid are two matrices that have been carefully studied and can provide insights into women's health. These matrices are clinically significant because they contain metabolites closely associated with women's illness stage and reproductive outcomes. Nowadays, the application of metabolomic analysis in biological matrices may be able to predict the outcome of assisted reproductive technologies with greater precision. From a molecular viewpoint on reproductive health, we evaluate and compare the utilization of human follicular fluid and blood as matrices in analysis for diagnostic and assisted reproductive technology (ART) predictors of success for endometriosis patients. In the follicular fluid (FF), plasma, and serum of endometriosis-affected women, researchers identified dysregulations of oxidative stress, upregulation of several immune factors, and aberrations in energy metabolic pathways. The altered signatures negatively correlate with the overall oocyte and embryo quality and fertilization rate.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.