Evidence map›Paper›PMID 39000246›Full record

ArticleInternational journal of molecular sciences2024

Long-Chain Alkylthio Cyclodextrin Derivatives for Modulation of Quorum-Sensing-Based Bioluminescence in

Éva Fenyvesi, Zsófia Berkl, Laura Ligethy, Ildikó Fekete-Kertész, Márton Csizmazia, Milo Malanga, István Puskás, Levente Szőcs, Róbert Iványi, István Kese and 3 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Éva FenyvesiCycloLab Cyclodextrin R&D Laboratory Ltd., Illatos út 7, 1097 Budapest, Hungary.ORCID 0000-0003-0609-7416
Zsófia BerklDepartment of Applied Biotechnology and Food Science, Budapest University of Technology and Economics, Műegyetem rkp. 3, 1111 Budapest, Hungary.ORCID 0000-0001-6354-1398
Laura LigethyDepartment of Applied Biotechnology and Food Science, Budapest University of Technology and Economics, Műegyetem rkp. 3, 1111 Budapest, Hungary.
Ildikó Fekete-KertészDepartment of Applied Biotechnology and Food Science, Budapest University of Technology and Economics, Műegyetem rkp. 3, 1111 Budapest, Hungary.ORCID 0000-0003-0757-1052
Márton CsizmaziaDepartment of Applied Biotechnology and Food Science, Budapest University of Technology and Economics, Műegyetem rkp. 3, 1111 Budapest, Hungary.
Milo MalangaCycloLab Cyclodextrin R&D Laboratory Ltd., Illatos út 7, 1097 Budapest, Hungary.
István PuskásCycloLab Cyclodextrin R&D Laboratory Ltd., Illatos út 7, 1097 Budapest, Hungary.ORCID 0000-0002-7879-2920
Levente SzőcsCycloLab Cyclodextrin R&D Laboratory Ltd., Illatos út 7, 1097 Budapest, Hungary.ORCID 0000-0002-9521-3628
Róbert IványiCycloLab Cyclodextrin R&D Laboratory Ltd., Illatos út 7, 1097 Budapest, Hungary.
István KeseCycloLab Cyclodextrin R&D Laboratory Ltd., Illatos út 7, 1097 Budapest, Hungary.ORCID 0009-0001-4717-613X
Erzsébet VargaCycloLab Cyclodextrin R&D Laboratory Ltd., Illatos út 7, 1097 Budapest, Hungary.
Lajos SzenteCycloLab Cyclodextrin R&D Laboratory Ltd., Illatos út 7, 1097 Budapest, Hungary.ORCID 0000-0002-7734-5440
Mónika MolnárDepartment of Applied Biotechnology and Food Science, Budapest University of Technology and Economics, Műegyetem rkp. 3, 1111 Budapest, Hungary.ORCID 0000-0001-5296-7924

Funding

Ministry for Innovation and Technology of Hungary from the National Research, Development, and Innovation Fund 2020-1.1.2-PIACI-KFI-2020-00092Ministry for Innovation and Technology of Hungary from the National Research, Development, and Innovation Fund NKFIH K_17 125093Ministry for Innovation and Technology of Hungary from the National Research, Development, and Innovation Fund, financed under the TKP2021 TKP2021-EGA-02
6 · The paper itself

Abstract

Quorum sensing (QS) allows bacteria to coordinate their activities by producing and detecting low-molecular-weight signal molecules based on population density, thereby controlling the infectivity of bacteria through various virulence factors. Quorum-sensing inhibition is a promising approach to tackle bacterial communication. Cyclodextrins (CDs) are a class of cyclic oligosaccharides that reversibly encapsulate the acyl chain of the signal molecules, thereby preventing their binding to receptors and interrupting bacterial communication. This results in the inhibition of the expression of various properties, including different virulence factors. To examine the potential quorum-quenching (QQ) ability of newly prepared cyclodextrin derivatives, we conducted short-term tests using

Indexed as

Aliivibrio fischeriCyclodextrinsQuorum SensingLuminescenceLuminescent MeasurementsCyclodextrinsAliivibrio fischerialkylthio cyclodextrinsbioluminescencequorum quenchingquorum sensing

Identifiers

PMID39000246
PMCPMC11241527

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.